FUNDAMENTALS OF BIOCHEMISTRY-ACCESS
5th Edition
ISBN: 9781119498742
Author: Voet
Publisher: WILEY
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Chapter 20, Problem 24E
Summary Introduction
To explain: The reason why the antidiabetes drug thiazolidinediones decreases the concentration of serum fatty acids, which are often elevated in diabetes.
Concept introduction: Thiazolidinediones are a class of medicines that can be used in the treatment of type 2 diabetes. These drugs are a type of oral hypoglycemic; that is, the medicine lowers blood glucose levels. It works on lowering the insulin resistance, which is the main problem in many people having type 2 diabetes.
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Draw a tripeptide of your choosing at pH 7. Have the N-terminus on the left and the C-terminus on the right. Then:
Draw a triangle around the α-carbons.
Draw a box around the R-groups.
Circle the atoms capable of hydrogen bonding.
Highlight the atoms involved in the formation of the peptide bonds.
What type of structure have you drawn? (primary, secondary, tertiary or quaternary protein structure).
2. For the flow of fluid over a flat membrane of length 10cm,
determine the length-average mass transfer coefficient. The
relevant properties of the system are u=0.01cm²/s, D=5 x 106
cm²/s, and v = 5.0 cm/s.
Background
Freezing isn't the only challenge in cryopreservation - thawing can
be just as difficult. A microwave oven seems like a nice solution,
since it deposits energy quickly and microwaves are non-ionizing
radiation (they do not cause DNA mutation). However, water
absorbs microwaves more effectively than ice does, meaning that
the portion of an organ that has already melted will get warmer at a
higher rate than the remaining ice – the opposite of what we want!
-
The transmission of radiation through a weakly absorbing material
such as ice or water can be modeled by Beer's law, which assumes
that the rate of absorption at a depth x is proportional to the local
radiation intensity I(x) times an absorption coefficient, which is often
written as μ or a or just µ). Noting that absorption decreases the
intensity, we can write a differential equation
a
Solving the differential equation with the boundary condition on the
surface being
gives the relationship
For a standard microwave oven…
Chapter 20 Solutions
FUNDAMENTALS OF BIOCHEMISTRY-ACCESS
Ch. 20 - Prob. 1ECh. 20 - 2. Identify die products generated by the action...Ch. 20 - 3. (a) What is. the charge of bile acids in the...Ch. 20 - 4. Bacteria that live in the large intestine...Ch. 20 - Prob. 5ECh. 20 - 6. Adipocytes store fat in phospholipid-coaled...Ch. 20 - Prob. 7ECh. 20 - Prob. 8ECh. 20 - 9. The first three steps of ? oxidation (Fig....Ch. 20 - Prob. 10E
Ch. 20 - Prob. 11ECh. 20 - Prob. 12ECh. 20 - Prob. 13ECh. 20 - 14. Short chain fatty acids such as butyrate are...Ch. 20 - 15. Why are unsaturated fats preferable to...Ch. 20 - 16. Calculate the ATP yield for the complete...Ch. 20 - 17. Explain why the degradation of odd-chain fatty...Ch. 20 - Prob. 18ECh. 20 - 19. Why is it important that liver cells lack...Ch. 20 - 20. An animal is fed palmitate with a 14C-labeled...Ch. 20 - 21. On what cartoon atoms docs the 14CO2 used to...Ch. 20 - Prob. 22ECh. 20 - 23. Explain why adipocytes need glucose as well as...Ch. 20 - Prob. 24ECh. 20 - 25. Pharmacological inhibition of acetyl-CoA...Ch. 20 - 26. Explain why inhibiting the activity of...Ch. 20 - Prob. 27ECh. 20 - 28. An animal is fed palmitate with a 14C-labeled...Ch. 20 - Prob. 29ECh. 20 - Prob. 30ECh. 20 - Prob. 31CQCh. 20 - Prob. 32CQCh. 20 - 33. Digestion of plant materials generates...Ch. 20 - Prob. 34CQCh. 20 - 35. The tricarboxylate transport system supplies...Ch. 20 - Prob. 36CQCh. 20 - 37. Compare the energy cost, in ATP equivalents,...Ch. 20 - Prob. 38CQCh. 20 - Prob. 39CQCh. 20 - Prob. 40CQCh. 20 - Prob. 41CQCh. 20 - Prob. 42CQCh. 20 - Prob. 43CQCh. 20 - Prob. 1MTE
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