(a) Interpretation: Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown. Concept introduction: The Gabriel synthesis is an effective way to synthesize a primary amine ( RNH 2 ) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Question

Want to see the full answer?

Answer 1

Question

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Reaction Fill-ins Part 2! Predict the product(s) OR starting material of the following reactions. Remember, Hydride shifts are possible if/when a more stable carbocation can exist (depending on reaction mechanism)! Put your answers in the indicated boxes d. d. ง HCI

A cylinder contains 12 L of water vapour at 150˚C and 5 atm. The temperature of the water vapour is raised to 175˚C, and the volume of the cylinder is reduced to 8.5 L. What is the final pressure of the gas in atmospheres? assume that the gas is ideal

On the next page is an LC separation of the parabens found in baby wash. Parabens are suspected in a link to breast cancer therefore an accurate way to quantitate them is desired. a. In the chromatogram, estimate k' for ethyl paraben. Clearly indicate what values you used for all the terms in your calculation. b. Is this a "good" value for a capacity factor? Explain. c. What is the resolution between n-Propyl paraben and n-Butyl paraben? Again, indicate clearly what values you used in your calculation. MAU | Methyl paraben 40 20 0 -2 Ethyl paraben n-Propyl paraben n-Butyl paraben App ID 22925 6 8 min

Answer 2

Question

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 6

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 7

Chapter 20, Problem 20.43P

Interpretation Introduction

(a)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide, followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 8

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 9

Interpretation Introduction

(b)

Interpretation:

Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.

Concept introduction:

The Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 10

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 11

Interpretation Introduction

(c)

Interpretation:

Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.

Concept introduction:

Gabriel synthesis is an effective way to synthesize a primary amine (RNH2) from an alkyl halide. In Gabriel synthesis, phthalimide is first treated with a strong base such as potassium hydroxide followed by an alkyl halide. Subsequent hydrolysis using hydroxide then liberates the primary amine. The alkyl halide used would be analogous to the primary amine target.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 15

Ch. 20 - Prob. 20.1P Ch. 20 - Prob. 20.2P Ch. 20 - Prob. 20.3P Ch. 20 - Prob. 20.4P Ch. 20 - Prob. 20.5P Ch. 20 - Prob. 20.6P Ch. 20 - Prob. 20.7P Ch. 20 - Prob. 20.8P Ch. 20 - Prob. 20.9P Ch. 20 - Prob. 20.10P

Solution Summary: The author explains that the Gabriel synthesis is an effective way to synthesize a primary amine from an alkyl halide.

Concept explainers

Videos

Want to see the full answer?

Chapter 20 Solutions