EBK GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260041255
Author: HARTWELL
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 20, Problem 11P
Two different protein complexes called SCF and APC covalently add a small polypeptide called ubiquitin to cyclin proteins. The addition of ubiquitin to a protein targets that protein to be degraded by another protein complex called the proteasome. The SCF complex is activated during S phase, and the APC complex is activated during M phase.
| a. | To which cyclins (A, B, D, or E in Fig. 20.14) do you think SCF couples ubiquitin? What about the APC? |
| b. | How might cells activate SCF and APC only at the correct times? |
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Chapter 20 Solutions
EBK GENETICS: FROM GENES TO GENOMES
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