ANATOMY & PHYSIOLOGY: AN INTEGRATIVE AP
3rd Edition
ISBN: 9781264013470
Author: McKinley
Publisher: MCGRAW-HILL LEARNING SOLN.(CC)
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Textbook Question
Chapter 19.7, Problem 29WDL
What three electrical events occur at the sarcolemma of cardiac muscle cells? Explain each event.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
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_____…
Chapter 19 Solutions
ANATOMY & PHYSIOLOGY: AN INTEGRATIVE AP
Ch. 19.1 - Prob. 1LOCh. 19.1 - WHAT DID YOU LEARN?
1 Define perfusion. Why would...Ch. 19.1 - Prob. 2LOCh. 19.1 - LEARNING OBJECTIVE
3. Describe the general...Ch. 19.1 - WHAT DO YOU THINK?
1 What vessels attached to the...Ch. 19.1 - Prob. 2WDLCh. 19.1 - Prob. 3WDLCh. 19.1 - Prob. 4WDLCh. 19.1 - Prob. 5WDLCh. 19.1 - Prob. 4LO
Ch. 19.1 - What path does blood follow through the heart?...Ch. 19.1 - Which of the great vessels is both an artery and...Ch. 19.2 - LEARNING OBJECTIVE
5. Describe the location and...Ch. 19.2 - Prob. 8WDLCh. 19.2 - Prob. 9WDLCh. 19.2 - Prob. 6LOCh. 19.2 - Prob. 7LOCh. 19.2 - Describe the three layers that cover the heart....Ch. 19.3 - LEARNING OBJECTIVE
8. Compare the superficial...Ch. 19.3 - Prob. 11WDLCh. 19.3 - Prob. 12WDLCh. 19.3 - Prob. 13WDLCh. 19.3 - Prob. 9LOCh. 19.3 - What are the layers of the heart (in order) that a...Ch. 19.3 - Prob. 10LOCh. 19.3 - What is the structure that separates the two...Ch. 19.3 - Prob. 16WDLCh. 19.3 - Prob. 11LOCh. 19.3 - What are the functions of the tendinous cords and...Ch. 19.3 - Prob. 12LOCh. 19.3 - Which function of the fibrous skeleton allows the...Ch. 19.3 - Prob. 13LOCh. 19.3 - Prob. 14LOCh. 19.3 - Prob. 15LOCh. 19.3 - Which features of cardiac muscle support aerobic...Ch. 19.4 - Prob. 16LOCh. 19.4 - Prob. 17LOCh. 19.4 - Prob. 18LOCh. 19.4 - Prob. 2WDTCh. 19.4 - What areas of the heart are deprived of blood when...Ch. 19.4 - Prob. 19LOCh. 19.4 - Prob. 21WDLCh. 19.5 - Prob. 20LOCh. 19.5 - Prob. 22WDLCh. 19.5 - Prob. 21LOCh. 19.5 - Which autonomic division is associated with the...Ch. 19.6 - LEARNING OBJECTIVE
22. Describe a nodal cell at...Ch. 19.6 - Prob. 24WDLCh. 19.6 - Prob. 23LOCh. 19.6 - Prob. 24LOCh. 19.6 - Prob. 3WDTCh. 19.6 - What is autorhythmicity? Describe how nodal cells...Ch. 19.6 - Prob. 25LOCh. 19.6 - What is the path of an action potential through...Ch. 19.6 - What anatomic features slow the conduction rate of...Ch. 19.7 - Prob. 26LOCh. 19.7 - In which direction does Ca2+ move in response to...Ch. 19.7 - Prob. 27LOCh. 19.7 - Prob. 28LOCh. 19.7 - Prob. 4WDTCh. 19.7 - What three electrical events occur at the...Ch. 19.7 - Prob. 29LOCh. 19.7 - Prob. 30LOCh. 19.7 - What is the significance of the extended...Ch. 19.7 - Prob. 31LOCh. 19.7 - What events in the heart are indicated by each of...Ch. 19.8 - Prob. 32LOCh. 19.8 - Prob. 33LOCh. 19.8 - Pressure changes that occur during the cardiac...Ch. 19.8 - Prob. 34LOCh. 19.8 - Prob. 35LOCh. 19.8 - What is occurring during ventricular ejection?Ch. 19.8 - Prob. 34WDLCh. 19.8 - Define end-diastolic volume, end-systolic volume,...Ch. 19.9 - Prob. 36LOCh. 19.9 - Prob. 37LOCh. 19.9 - What are the two factors that determine cardiac...Ch. 19.9 - What is the cardiac output at rest and during...Ch. 19.9 - Prob. 38LOCh. 19.9 - Prob. 39LOCh. 19.9 - Prob. 38WDLCh. 19.9 - Describe the atrial reflex, which involves...Ch. 19.9 - Prob. 40LOCh. 19.9 - Prob. 41LOCh. 19.9 - Prob. 40WDLCh. 19.9 - Prob. 42LOCh. 19.9 - Prob. 41WDLCh. 19.10 - Prob. 43LOCh. 19.10 - Prob. 44LOCh. 19.10 - Prob. 42WDLCh. 19 - Which of the following is the correct circulatory...Ch. 19 - The pericardial cavity is located between the a....Ch. 19 - How is blood prevented from backflowing from the...Ch. 19 - ____ 4. Venous blood draining from the heart wall...Ch. 19 - _____ 5. Calcium channels in the nodal cells...Ch. 19 - ____6. Action potentials are spread rapidly...Ch. 19 - Why is it necessary to stimulate papillary muscles...Ch. 19 - ____ 8. Preload is a measure of a. stretch of...Ch. 19 - ____ 9. All of the following occur when the...Ch. 19 - ____10. What occurs during the atrial reflex? a....Ch. 19 - Prob. 11DYBCh. 19 - Compare the structure, location, and function of...Ch. 19 - Prob. 13DYBCh. 19 - Explain why the walls of the atria are thinner...Ch. 19 - Describe the structure and function of...Ch. 19 - Explain the general location and function of...Ch. 19 - Describe the functional differences in the effects...Ch. 19 - Prob. 18DYBCh. 19 - List the five events of the cardiac cycle, and...Ch. 19 - Define cardiac output, and explain how it is...Ch. 19 - A young man was doing some vigorous exercise when...Ch. 19 - A young man was doing some vigorous exercise when...Ch. 19 - Prob. 3CALCh. 19 - Prob. 4CALCh. 19 - During surgery, the right vagus nerve was...Ch. 19 - Prob. 1CSLCh. 19 - Prob. 2CSLCh. 19 - Your grandfather was told that his SA node...
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