The reason behind the rotenone being lethal to some insects and fishes. Introduction : There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

The standard cost of Product B manufactured by Oriole Company includes 3.5 units of direct materials at $5.40 per unit. During June, 27,300 units of direct materials are purchased at a cost of $5.15 per unit, and 27,300 units of direct materials are used to produce 7,600 units of Product B. (a) Compute the total materials variance and the price and quantity variances. Total materials variance Materials price variance Materials quantity variance $ (b) Compute the total materials variance and the price and quantity variances, assuming the purchase price is $6.35 and the quantity purchased and used is 26,300 units. Total materials variance Materials price variance Materials quantity variance $

The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form acetyl CoA. E₁, E2, and E3 are abbreviations for the enzymes of the complex. Classify the enzyme names, prosthetic groups, and reactions as E1, E2, or E3. E₁ E2 Answer Bank E3 transfer of electrons to FAD and then to NAD+ transfer of acetyl group to coenzyme A formation of hydroxyethyl-TPP hydroxyethyl group transferred to lipoamide thiamine pyrophosphate (TPP) FAD lipoamide dihydrolipoyl transacetylase pyruvate dehydrogenase dihydrolipoyl dehydrogenase

Patients with pyruvate dehydrogenase deficiency show high levels of lactic acid in the blood. However, in some cases, treatment with dichloroacetate (DCA), which inhibits the kinase associated with the pyruvate dehydrogenase complex, lowers lactic acid levels. How does DCA act to stimulate pyruvate dehydrogenase activity? DCA activates pyruvate dehydrogenase kinase. DCA increases phosphorylation levels of pyruvate dehydrogenase. DCA inhibits pyruvate dehydrogenase kinase. ODCA activates pyruvate dehydrogenase phosphatase. What does this suggest about pyruvate dehydrogenase activity in patients who respond to DCA? The pyruvate dehydrogenase complex is active only when phosphorylated by the kinase. The pyruvate dehydrogenase complex is active only in the presence of the kinase. The pyruvate dehydrogenase complex is completely inactive. The pyruvate dehydrogenase complex displays some residual activity.

Answer 2

Question

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Answer 6

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

Answer 7

Chapter 19, Problem 5P

(a)

Summary Introduction

To explain:

The reason behind the rotenone being lethal to some insects and fishes.

Introduction:

There are several agents that intervene with oxidative phosphorylation. Depending on the type of interference they are classified as the agents that inhibit transfer of electron, agents that inhibit ATP (adenosine triphosphate) synthase, agent that uncouple phosphorylation from electron transfer and agents that inhibit ATP-ADP (adenosine diphosphate) exchange.

Answer 8

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

Answer 9

(b)

Summary Introduction

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

Answer 10

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Answer 11

(c)

Summary Introduction

To explain:

Whether rotenone or antimycin A is more poisonous.

Introduction:

Rotenone and antimycin both are inhibitors of electron transport chain. Rotenone inhibits the flow of electron to complex I and antimycin inhibits the flow of electron from complex II to complex III. The potency of inhibitors depend on the complex which is blocked.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 15

Ch. 19 - Prob. 1P Ch. 19 - Prob. 2P Ch. 19 - Prob. 3P Ch. 19 - Prob. 4P Ch. 19 - Prob. 5P Ch. 19 - Prob. 6P Ch. 19 - Prob. 7P Ch. 19 - Prob. 8P Ch. 19 - Prob. 9P Ch. 19 - Prob. 10P

Concept explainers

Videos

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

Want to see the full answer?

Chapter 19 Solutions

Concept explainers

Videos

To explain: The reason behind antimycin A being poisonous. Introduction: Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.

Want to see the full answer?

Chapter 19 Solutions

To explain:

The reason behind antimycin A being poisonous.

Introduction:

Agents that inhibit the transfer of electrons are known as inhibitors of electron transport chain. Some of the examples of inhibitors are rotenone, antimycin A, amytal, piericidin A, cyanide, and carbon monoxide.