SAPLINGPLUS FOR PRINCIPLES OF BIOCHEMIS
7th Edition
ISBN: 9781319424572
Author: nelson
Publisher: MAC HIGHER
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Chapter 19, Problem 23P
Summary Introduction
To explain: The difference between milder and severe form of disease caused by presence of one and two defective copies of glucokinase gene respectively.
Introduction:
One isozyme of hexokinase is glucokinase. Glucokinase is an enzyme which catalyzes phosphorylation of glucose. Phosphorylation of glucose is the first reaction in glycolysis. Glucokinase is present in pancreas and liver. When glucose is present in high amounts in the cell, it converts it into glucose-6-phosphate, which enters glycolysis.
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2
Br
OCH₁₂
CF3
3
4
2. Which one shows the correct order of reactivity of these four compounds in
electrophilic aromatic substitution reactions, with more reactive > least reactive ?
A) 1>2>3>4
B) 13>4> 2
C) 3 > 2 > 1 > 4 D) 4 > 3 > 1 > 2 E) 3 >1>2> 4
12. Which of the compounds
below is expected to be the
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COOH
Br
A
C₂H5CI
H₂CrO4
Br₂
FeBr3
AICI 3
.COOH
.COOH
COOH
CH₂OH
B
Br
Br
C
D
Br
E
Br
11. Which of these chlorobenzenes does not undergo nucleophilic aromatic
substitution upon treatment with NaNH2?
CI
CI
CI
CI
CI
A
B
C
D
E
Chapter 19 Solutions
SAPLINGPLUS FOR PRINCIPLES OF BIOCHEMIS
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