Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 19, Problem 5MCQ
Summary Introduction
Introduction:
Chronic form of meningitis is caused by Cryptococcus neoformans. The symptoms arise gradually. The most common symptom is headache; however, neck stiffness and nausea are other symptoms.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 19 Solutions
Microbiology: A Systems Approach
Ch. 19.1 - Describe the important anatomical features of the...Ch. 19.1 - Prob. 2AYPCh. 19.2 - Discuss the current state of knowledge regarding...Ch. 19.3 - Prob. 4AYPCh. 19.3 - Prob. 5AYPCh. 19.3 - Discuss important features of meningoencephalitis,...Ch. 19.3 - Prob. 7AYPCh. 19.3 - Prob. 8AYPCh. 19.3 - Prob. 9AYPCh. 19.3 - Prob. 10AYP
Ch. 19 - Prob. 1MCQCh. 19 - Prob. 2MCQCh. 19 - Meningococcal meningitis is caused by a....Ch. 19 - Prob. 4MCQCh. 19 - Prob. 5MCQCh. 19 - Prob. 6MCQCh. 19 - Prob. 7MCQCh. 19 - Prob. 8MCQCh. 19 - Prob. 9MCQCh. 19 - Prob. 10MCQCh. 19 - Prob. 11TFCh. 19 - Prob. 12TFCh. 19 - Prob. 13TFCh. 19 - Prob. 14TFCh. 19 - Prob. 15TFCh. 19 - Prob. 1CTQCh. 19 - Prob. 2CTQCh. 19 - Prob. 3CTQCh. 19 - Prob. 4CTQCh. 19 - Prob. 5CTQCh. 19 - Prob. 1VCCh. 19 - Prob. 1CM
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