GENETICS:FROM GENES TO GENOMES(LL)-PKG
GENETICS:FROM GENES TO GENOMES(LL)-PKG
6th Edition
ISBN: 9781260377033
Author: HARTWELL
Publisher: MCG
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Chapter 19, Problem 34P

The Drosophila even-skipped (eve) gene has four different enhancers that control its transcription in a pattern of seven stripes. (One of them—the stripe 2 enhancer—is shown in Fig. 19.23c.)

a. Why is the stripe 2 enhancer active only in cells corresponding to stripe 2?
b. The other three enhancers each work in the cells corresponding to two different (nonadjacent) stripes. How is this possible?
c. Secondary pair-rule genes like ftz have only one enhancer that is active in all seven stripes. How is this possible? Describe an experiment that would have led scientists to this conclusion.
d. Would you expect the segment polarity gene engrailed to have two enhancers or fourteen enhancers, one active in each stripe?
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Chapter 19 Solutions

GENETICS:FROM GENES TO GENOMES(LL)-PKG

Ch. 19 - Drosophila researchers have collected many strains...Ch. 19 - As an alternative to random mutagenesis,...Ch. 19 - A C. elegans nematode gene called par-1 helps to...Ch. 19 - The molecular identity of the fruit fly rugose...Ch. 19 - To determine the focus of action of boss,...Ch. 19 - Suppose a particular gene is required for early...Ch. 19 - Researchers have exploited Minute mutations in...Ch. 19 - Some ts alleles are temperature sensitive during...Ch. 19 - The following figure shows the temperature-shift...Ch. 19 - A temperature-sensitive allele of the gene...Ch. 19 - Hypomorphic alleles of a pleiotropic gene...Ch. 19 - In addition to the maternal effect genes that...Ch. 19 - The yan gene encodes a transcription factor that...Ch. 19 - Recall from Chapter 17 that in Drosophila, sex...Ch. 19 - a. Explain the difference between maternal...Ch. 19 - In the 1920s, Arthur Boycott, working with the...Ch. 19 - The Drosophila mutant screen shown on the...Ch. 19 - Some genes are required both zygotically and...Ch. 19 - How would a human with a mutation in a maternal...Ch. 19 - One important demonstration that Bicoid is an...Ch. 19 - The hunchback gene contains a 5 transcriptional...Ch. 19 - In flies developing from eggs laid by a...Ch. 19 - Wild-type embryos and mutant embryos lacking the...Ch. 19 - The Drosophila even-skipped eve gene has four...Ch. 19 - In Drosophila with loss-of-function mutations...Ch. 19 - It is crucial to the development of Drosophila...Ch. 19 - In the plant Arabidopsis thaliana, every flower is...
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