EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
7th Edition
ISBN: 9780133983401
Author: Silverthorn
Publisher: YUZU
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Chapter 19, Problem 21RQ

Draw a section of renal tubule epithelium showing three cells joined by cell junctions. Label the apical and basolateral membranes, the tubule lumen, and the extracellular fluid. Use the following written description of proximal tubule processes to draw a model cell.

The proximal tubule cells contain carbonic anhydrase, which promotes the conversion of CO2 and water H+ and HCO3. Sodium is reabsorbed by an apical Na+-H+ antiporter and a basolateral Na+-K+-ATPase. Chloride is passively reabsorbed by movement through the paracellular pathway. Bicarbonate produced in the cytoplasm leaves the cell on a basolateral Na+-HCO3 symporter.

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EBK HUMAN PHYSIOLOGY

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