Concept explainers
What is chromatin?
a. the histone-containing protein core of the nucleosome
b. the 30-nm fiber
c. the complex of DNA and proteins found in the nucleus
d. the histone and non-histone proteins in eukaryotic nuclei
Introduction:
Chromatin is mostly found in the cells, comprising of the DNA (deoxyribonucleic acid), RNA (ribonucleic acid), and protein. There are three levels of chromatin organization, namely, euchromatin, heterochromatin, and high-level DNA packaging of the fiber into the metaphase chromosome.
Answer to Problem 1TYK
Correct answer:
The DNA and histone together form chromatin. The packaging of the double helical structure of DNA is done by the histones.
Explanation of Solution
Explanation/Justification for the correct answer:
Option (c) is given as the assemblage of proteins and DNA in the nucleus is called chromatin. A gene expresses itself in a number of stages in a cell. These stages are transcription and translation. Prior to transcription, the DNA remains bound with proteins in the nucleus and is called as chromatin. Hence, Option (c) is correct.
Explanation for incorrect answers:
Option (a) is given as the histone that contains the protein core of the nucleosome. The nucleosome is a part of DNA with its proteins, which consists of a small segment of DNA held together by histone proteins. This is a part of chromatin and its repeated units give rise to complete chromatin. So, it is an incorrect option.
Option (b) is given as the 30-nm fiber. The H1 histones interact with one another and with the histone proteins in the adjacent nucleosome providing them a regular position. This structure is called as 30-nm (nanometer) fiber. So, it is an incorrect option.
Option (d) is given as the histone and non-histone proteins present in the nuclei of the eukaryotic cells. The proteins that bind DNA in the nucleus in eukaryotic cells are called histones. They are a part of chromatin. The proteins other than the histone proteins in the chromatin like DNA polymerase, scaffold proteins, polycomb proteins, and heterochromatin protein 1 are called as non-histone proteins. So, it is an incorrect option.
Hence, options (a), (b), and (d) are incorrect.
The main function of the chromatin is to effectively package the DNA into a small area in order to fit the DNA into the nucleus of the cell. It also protects the structure and sequence of the DNA.
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Chapter 19 Solutions
Biological Science
- Which of the following represents the order of increasingly higher levels of organization of chromatin? Select one: O a. looped domain, nucleosome, 30-nm chromatin fiber O b. 30-nm chromatin fiber, nucleosome, looped domain C. nucleosome, looped domain, 30-nm chromatin fiber O d. looped domain, 30-nm chromatin fiber, nucleosome nucleosome, 30-nm chromatin fiber, looped domain е.arrow_forwardhow is the structure of chromatin loops beneficial to a cell?arrow_forwardWhich histone helps stabilize the solenoid structure of eukaryotic chromatin? H4 H3 H2B H2A H1arrow_forward
- Loosening the chromatin structure occurs because of Select one: a. Lysine methylation b. Lysine acetylation c. Lysine phosphorylation d. Lysine sumoylationarrow_forwardWhich of the following is associated with active chromatin? Check all that apply. A. Centromeres B. heterochromatin C. histone acetylation D. Polytene puffs E. metaphase chromasomes F. transcription of machineryarrow_forwardThe DNA in a cell associates with proteins to form chromatin. What is a nucleosome?arrow_forward
- A nucleosome consists of (a) DNA and scaffolding proteins (b) scaffolding proteins and histones (c) DNA and histones (d) DNA, histones, and scaffolding proteins (e) histones onlyarrow_forwardBiologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.arrow_forward(a)Discuss or explain the consequences for a cell if the chromatin could not be remodeled. (b) Does the action of the telemorase enzyme contradict the central dogma of molecular biology? why or why not?arrow_forward
- Describe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.arrow_forwardWhich of these is NOT true of nucleosomes? A. Some post-translational modifications to histone proteins serve as binding sites for transcription factors. B. The position of nucleosomes is fixed on the genome and can not be changed. C. The position and post-translational modifications of histones can be inherited through mitosis. D. The binding between DNA and histone proteins can be disrupted by post-translational modifications.arrow_forwardNumber 6arrow_forward
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