Videos
To analyze :
The characteristics of bacteria that contribute to the development of antibiotic resistance.
Introduction :
Bacteria also possess small extrachromosomal, self-replicating, double-stranded, circular DNA apart from chromosomal DNA. R-plasmids carry genes for resistance against antibiotics. They can pass from one bacterium to another through horizontal gene transfer. This transfer of resistance results in the spread of resistance to the neighboring bacterial cells. Through this primary mechanism, bacteria evolve themselves to degrade the novel compounds such as drugs by acquiring resistance. It results in a medically challenging condition to deal with.
Explanation of Solution
Antibiotics eliminate the pathogenic bacteria either by killing it or by inhibiting its growth. However, bacteria are capable of acquiring resistance against antibiotics through horizontal gene transfer. It is a non-genealogical transmission of the genes coding for antibiotic resistance in the neighboring bacteria. These genes are mostly located on bacterial plasmid through which the resistance is spread. Methods through which resistance genes can be transferred horizontally are conjugation, transformation, and transduction. Most commonly, a bacterial cell spread resistivity through conjugation. The pili present on the surface of the bacterial cell helps to form a conjugation tube between a donor and recipient bacterial cell. Through the conjugation tube, the genes for resistance are transferred to the neighboring bacterial cells. All these methods involve passing of the traits from the donor cell to the recipient cell that results in alteration of the genetics of a competent bacterial cell.
Apart from this, bacteria can also acquire resistance because of mutation caused due to selective pressure of antibiotic use. A high rate of replication is the cause of these genetic mutations. The faster the rate of replication, the faster the chances of acquiring the changes in the genome according to the changing environment. Bacteria evolve and adapt to antibiotics to survive in a hostile environment. The rate of acquiring resistance is also very high. Once it acquires resistance to first-line antibiotics, it further becomes resistant to second and third-line drugs too. It leads to the development of multi-drug resistant conditions.
Bacteria acquire drug resistance through horizontal gene transfer. They commonly transfer the genes for resistance present on the plasmid through conjugation. The pilus forms a conjugation tube and the genes are transferred from the donor cell to the recipient cell. It causes the spread of resistivity. They can also evolve due to selective pressure to survive in a hostile environment that contains antibiotics. They acquire changes in their genome and evolve to gain resistivity against antibiotics.
Chapter 19 Solutions
Glencoe Biology, Florida Edition
Additional Science Textbook Solutions
Microbiology with Diseases by Body System (5th Edition)
Human Physiology: An Integrated Approach (8th Edition)
Campbell Biology: Concepts & Connections (9th Edition)
Campbell Biology (11th Edition)
Applications and Investigations in Earth Science (9th Edition)
Introductory Chemistry (6th Edition)
- Please finish the chart at the bottom. Some of the answers have been filled in.arrow_forward9. Aerobic respiration of one lipid molecule. The lipid is composed of one glycerol molecule connected to two fatty acid tails. One fatty acid is 12 carbons long and the other fatty acid is 18 carbons long in the figure below. Use the information below to determine how much ATP will be produced from the glycerol part of the lipid. Then, in part B, determine how much ATP is produced from the 2 fatty acids of the lipid. Finally put the NADH and ATP yields together from the glycerol and fatty acids (part A and B) to determine your total number of ATP produced per lipid. Assume no other carbon source is available. 18 carbons fatty acids 12 carbons 9 glycerol A. Glycerol is broken down to glyceraldehyde 3-phosphate, a glycolysis intermediate via the following pathway shown in the figure below. Notice this process costs one ATP but generates one FADH2. Continue generating ATP with glyceraldehyde-3-phosphate using the standard pathway and aerobic respiration. glycerol glycerol-3- phosphate…arrow_forwardNormal dive (for diving humans) normal breathing dive normal breathing Oz level CO2 level urgent need to breathe Oz blackout zone high CO2 triggers breathing 6. This diagram shows rates of oxygen depletion and carbon dioxide accumulation in the blood in relation to the levels needed to maintain consciousness and trigger the urgent need to breathe in diving humans. How might the location and slope of the O₂ line differ for diving marine mammals such as whales and dolphins? • How might the location and slope of the CO₂ line differ for diving marine mammals such as whales and dolphins? • • Draw in predicted lines for O2 and CO2, based on your reasoning above. How might the location of the Urgent Need to Breathe line and the O2 Blackout Zone line differ for diving marine mammals? What physiological mechanisms account for each of these differences, resulting in the ability of marine mammals to stay submerged for long periods of time?arrow_forward
- foraging/diet type teeth tongue stomach intestines cecum Insectivory numerous, spiky, incisors procumbentExample: moleExample: shrew -- simple short mostly lacking Myrmecophagy absent or reduced in numbers, peg-likeExample: tamandua anteater extremely long simple, often roughened short small or lacking Terrestrial carnivory sharp incisors; long, conical canines; often carnassial cheek teeth; may have crushing molarsExample: dog -- simple short small Aquatic carnivory homodont, spiky, numerousExample: common dolphin -- simple or multichambered (cetaceans only) variable small or absent Sanguinivory very sharp upper incisors; reduced cheek teethExample: vampire bat grooved tubular, highly extensible long small or lacking Herbivory (except nectivores) incisors robust or absent; canines reduced or absent; diastema; cheek teeth enlarged with complex occlusal surfacesExample: beaver -- simple (hindgut fermenters) or multichambered (ruminants) long large Filter feeding none…arrow_forward3. Shown below is the dental formula and digestive tract anatomy of three mammalian species (A, B, and C). What kind of diet would you expect each species to have? Support your answers with what you can infer from the dental formula and what you can see in the diagram. Broadly speaking, what accounts for the differences? Species A 3/3, 1/1, 4/4, 3/3 པར『ན་ cm 30 Species B 4/3, 1/1, 2/2, 4/4 cm 10 Species C 0/4, 0/0,3/3, 3/3 020arrow_forward3. Shown below is the dental formula and digestive tract anatomy of three mammalian species (A, B, and C). What kind of diet would you expect each species to have? Support your answers with what you can infer from the dental formula and what you can see in the diagram. Broadly speaking, what accounts for the differences? Species A 3/3, 1/1, 4/4, 3/3 cm 30 Species B 0/4, 0/0, 3/3, 3/3 cm 10 Species C 4/3, 1/1, 2/2, 4/4 E 0 cm 20 AILarrow_forward
- Normal dive (for diving humans) normal breathing dive normal breathing Oz level CO₂ level urgent need to breathe Oz blackout zone high CO₂ triggers breathing 6. This diagram shows rates of oxygen depletion and carbon dioxide accumulation in the blood in relation to the levels needed to maintain consciousness and trigger the urgent need to breathe in diving humans. • How might the location and slope of the O2 line differ for diving marine mammals such as whales and dolphins? • How might the location and slope of the CO2 line differ for diving marine mammals such as whales and dolphins? • • Draw in predicted lines for O2 and CO2, based on your reasoning above. How might the location of the Urgent Need to Breathe line and the O2 Blackout Zone line differ for diving marine mammals? What physiological mechanisms account for each of these differences, resulting in the ability of marine mammals to stay submerged for long periods of time?arrow_forwardHow much ATP will be produced during the following metabolic scenario: Aerobic respiration of a 5mM lipid solution that is made up of one glycerol and an 8-carbon fatty acid and 12-carbon fatty acid. Recall that when glycerol breaks down to Glyceraldehyde-3-phosphate it costs one ATP but your get an extra FADH2. Every two carbons of a fatty acid break down to one acetyl-CoA. Units cannot be entered in this style of question but the units of your answer should be in mM of ATP.arrow_forwardIf a bacterium using aerobic respiration was to degrade one small protein molecule into 8 molecules of pyruvic acid, how many ATP would that cell make? Assume there is no other carbon source. Units cannot be entered in this style of question but the units of your answer should be in molecules of ATP.arrow_forward
- If a bacterium using aerobic respiration was to degrade a 30 mM solution of citric acid, how many ATP would that cell make? Assume no other carbon source is available. Units cannot be entered in this style of question but the units of your answer should be in mM of ATP.arrow_forwardHow much ATP will be produced during the following metabolic scenario: Aerobic respiration of a 5mM lipid solution that is made up of one glycerol and an 8-carbon fatty acid and 12-carbon fatty acid. Recall that when glycerol breaks down to Glyceraldehyde-3-phosphate it costs one ATP but your get an extra FADH2. Every two carbons of a fatty acid break down to one acetyl-CoA. (pathways will be provided on the exam) Units cannot be entered in this style of question but the units of your answer should be in mM of ATP.arrow_forwardWhen beta-lactamase was isolated from Staphylcoccus aureus and treated with a phosphorylating agent, only the active site, serine was phosphorylated. Additionally, the serine was found to constitute 0.35% (by weight) of this beta-lactamase enzyme. Using this, calculate the molecular weight of this enzyme and estimate the number of amino acids present in the polypeptide.arrow_forward
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education