PRESCOTT'S MICROBIO W/PROCTORIO
11th Edition
ISBN: 9781264731060
Author: WILLEY
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Textbook Question
Chapter 18.5, Problem 1MI
Figure 18.12 Metabolic Pathways and Transport Systems of Treponema pallidum. This depicts T. pallidum
Based on this genomic reconstruction, can you determine if T. pallidum has a respiratory or fermentative metabolism?
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
a. What is the function of bactoprenol in peptidoglycan synthesis?
b. During peptidoglycan synthesis, removal of a phosphate group from bactoprenol pyrophosphate is
inhibited. What is the immediate outcome? What does this mean for cell wall synthesis? Which
antibiotic works via this mechanism?
c. Bacterium Y is photosynthetic. You want to decrease the ability of Bacterium Y to produce glucose
through photosynthesis. Explain how you could manipulate the light reactions of photosynthesis to
decrease glucose production during the dark reactions in Bacterium Y. Include the name of the
pathway that makes glucose during the dark reactions, which/how molecules from the light
reactions are used in this pathway, and what specific steps of this pathway would be affected by
your manipulations.
Peroxidase is an enzyme found in many organisms, from plant to humans. The function of peroxidase is to break down hydrogen peroxide, which is a toxin produced as a byproduct when oxygen is
produced during respiration. Myeloperoxidase is a protein found in neutrophils and catalyzes lipid peroxidation involved in immune defense. The overproduction of myeloperoxidase has been found to
function as a mediator for tissue damage in inflammatory diseases. (8 points)
a. Identify two examples of environmental factors that may impact myeloperoxidase activity. Describe how each of the environmental factors would affect the reaction rate of the enzyme.
b. Predict the how researchers can use myeloperoxidase activity as oxidative stress biomarkers in patients with rheumatoid arthritis. Provide reasoning to justify your prediction.
Yarrowia lipolytica(Yl) is a non-conventional yeast that diverged from baker’s yeast, Saccharomyces cerevisiae(Sc), early in evolutionary history. The regulation of glycolytic enzymes in Yl differs from that of Sc. The figures below show how PFK activity is affected by fructose-2,6-bisphosphate and phosphoenolpyruvate. Based on these data, which molecule is the major regulator of PFK activity in each species?
Chapter 18 Solutions
PRESCOTT'S MICROBIO W/PROCTORIO
Ch. 18.1 - MICRO INQUIRY What is the function of the 3-OH...Ch. 18.1 - MICRO INQUIRY Why is it important that identical...Ch. 18.2 - MICRO INQUIRY Which step (or steps) in this...Ch. 18.2 - Retrieve, Infer, Apply Why is the Sanger technique...Ch. 18.2 - Retrieve, Infer, Apply Explain the difference...Ch. 18.2 - Retrieve, Infer, Apply Why does reversible chain...Ch. 18.2 - Prob. 4CCCh. 18.2 - Retrieve, Infer, Apply Suggest a medical and an...Ch. 18.3 - Retrieve, Infer, Apply NGS techniques are...Ch. 18.3 - Retrieve, Infer, Apply Examine figure 18.8. How...
Ch. 18.4 - Prob. 1MICh. 18.4 - Prob. 1CCCh. 18.4 - Prob. 2CCCh. 18.4 - Prob. 3CCCh. 18.5 - Figure 18.12 Metabolic Pathways and Transport...Ch. 18.5 - Prob. 2MICh. 18.5 - Prob. 3MICh. 18.5 - Prob. 1CCCh. 18.5 - Retrieve, Infer, Apply How might the following...Ch. 18.5 - Retrieve, Infer, Apply Compare and contrast...Ch. 18.5 - Retrieve, Infer, Apply Why does two-dimensional...Ch. 18.5 - Retrieve, Infer, Apply What is the difference...Ch. 18.5 - Retrieve, Infer, Apply Describe a ChIP-Seq...Ch. 18.7 - Prob. 1MICh. 18.7 - Retrieve, Infer, Apply Cite an infectious disease...Ch. 18.7 - Prob. 2CCCh. 18.7 - Prob. 3CCCh. 18 - Prob. 1RCCh. 18 - Prob. 2RCCh. 18 - Prob. 3RCCh. 18 - Prob. 4RCCh. 18 - Prob. 5RCCh. 18 - Prob. 1ALCh. 18 - Prob. 2ALCh. 18 - You are developing a new vaccine for a pathogen....Ch. 18 - Prob. 4AL
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The pathway for cystiene synthesis in E.coli involves five precursor compounds, compound A-E. The requirements for each of the autotrophs are summarized in the table below. Use the data, define the biosynthetic pathway. Draw the pathway for cysteine synthesis. Fill in the blanks with A-E compounds as appropriate and then label the arrows with the auxotrophs C1-C8 that are unable to complete that step. There are may be more than one quxotroph that is defective at a particular step. that is - on C4 in Darrow_forwardIn the presence of oxygen, the mitochondrion in yeast is used for aerobic respiration,however, under anaerobic conditions,the yeast mitochondria have been found to have other function. Identify and briefly discuss four of these functionsarrow_forwardYarrowia lipolytica(Yl) is a non-conventional yeast that diverged from baker’s yeast, Saccharomyces cerevisiae(Sc), early in evolutionary history. The regulation of glycolytic enzymes in Yl differs from that of Sc. The data below pertain to regulation of phosphofructokinase 1 (PFK). Data for Yl is shown with black circles and data for Sc is shown with white circles. Pfk for both species is a homo-octomer (eight identical subunits). Given the data below, which species is more likely to be susceptible to allosteric modification? Briefly explain.arrow_forward
- Yarrowia lipolytica(Yl) is a non-conventional yeast that diverged from baker’s yeast, Saccharomyces cerevisiae(Sc), early in evolutionary history. The regulation of glycolytic enzymes in Yl differs from that of Sc. The data below pertain to regulation of phosphofructokinase 1 (PFK). Data for Yl is shown with black circles and data for Sc is shown with white circles. Imagine that the genes for phosphofructose kinase 2 and fructose 2,6-bisphosphatase were deleted in each species. Which species would you expect to have greater metabolic disruption and why?arrow_forwardFor each of the following mutant E. coli strains,plot a 30-minute time course of concentration ofβ-galactosidase, permease, and acetylase enzymesgrown under the following conditions: For the first10 minutes, no lactose is present; at 10 minutes, lactosebecomes the sole carbon source. Plot concentration onthe y-axis, time on the x-axis. (Don’t worry about theexact units for each protein on the y-axis.)a. I− P+ o+ Z+ Y+ A+ / I+ P+ o+ Z− Y+ A+b. I− P+ ocZ+ Y+ A− / I+ P+ o+ Z− Y+ A+c. IsP+ o+ Z+ Y+ A+ / I− P+ o+ Z− Y+ A+d. I− P− o+ Z+ Y+ A+ / I− P+ ocZ+ Y− A+e. I− P+ o+ Z− Y+ A+ / I− P− ocZ+ Y− A+arrow_forwardLeigh syndrome is characterized by psychomotor regression: that is, the progressive loss of mental andmovement abilities. Patients also suffer from lacticacidosis, a condition in which mitochondrial respiration is deficient, so their tissues metabolize glucoseanaerobically, leading to the buildup of lactate. Somepatients with Leigh syndrome have a mutation in themitochondrial gene MT-CO3, which encodes a subunit of the electron transport complex cytochromec oxidase. Other patients diagnosed with Leigh syndrome have a loss-of-function mutation in the nucleargene SURF1, which encodes a factor needed for theassembly of this same enzyme complex.a. How can the same symptoms result from mutationsin a mitochondrial gene and from mutations in anuclear gene?arrow_forward
- Complex II contains one heme b moiety that is not in the direct path of electron transfer (despite what many figures found on the internet show). It may serve instead to decrease the frequency with which electrons leak out of the system to produce reactive oxidative species (ROS). Discuss the correlation between a defective heme b in Complex II and the development of certain types of cancer. Name some of the ROS and give their structures. How are ROS generated? What are some of the mechanisms by which the oxidative stress caused by ROS is alleviated? What are some of the damaging effects of ROS? How might these damaging effects lead to cancer?arrow_forwardResearchers isolated a yeast phosphofructokinase (PFK) mutant in which a serine at the fructose-2,6-bisphosphate binding site was replaced with an aspartate residue. The amino acid substitution completely abolished the binding of fructose-2,6-bisphosphate to PFK. There was a dramatic decline in glucose consumption and ethanol production in the mutant compared to control yeast. What does the decline of glucose consumption and ethanol production in the yeast show about the function of fructose-2,6-bisphosphate in glycolysis?arrow_forwardAbout the process of industrial production of ethanol by the yeast Saccharomyces cerevisiae, mark the correct alternatives: (a) the cells must be cultured in anaerobic conditions to activate the metabolic pathway of ethanol production (b). the presence of oxygen is required to allow regeneration of the NAD+ cofactor (c). good oxygenation of the medium is important to favor the formation of greater amounts of ATP (d).the production of ethanol is always accompanied by the formation of glycerol (e). the sugar present in the culture medium is completely oxidized to CO2 and waterarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Parasites: Protozoa (classification, structure, life cycle); Author: ATP;https://www.youtube.com/watch?v=V4iSB0_7opM;License: Standard youtube license