Anatomy & Physiology: The Unity of Form and Function
8th Edition
ISBN: 9781259277726
Author: Kenneth S. Saladin Dr.
Publisher: McGraw-Hill Education
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Chapter 18, Problem 6TYR
Summary Introduction
Introduction:
The two fundamental physical properties of blood are its viscosity and osmolarity. Both are tightly regulated by homeostasis as survival measures. Blood viscosity determines flow through blood vessels. When blood viscosity rises, even thrice higher than normal as seen in primary polycythemia, flow in blood vessels gets sluggish and capillaries are plugged due to the highly viscous fluid. This decreases circulation and overloads the heart’s pumping function. Heart failure and stroke are a usual consequence of chronically high blood viscosity.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
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A. Dose; Increase dose
B. Dose; Decrease dose
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E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 18 Solutions
Anatomy & Physiology: The Unity of Form and Function
Ch. 18.1 - Identify at least two each of the transport,...Ch. 18.1 - Prob. 2BYGOCh. 18.1 - List the three major classes of plasma proteins....Ch. 18.1 - Prob. 4BYGOCh. 18.1 - Prob. 5BYGOCh. 18.1 - Prob. 1AYLOCh. 18.1 - Prob. 2AYLOCh. 18.1 - Prob. 3AYLOCh. 18.1 - Prob. 4AYLOCh. 18.1 - Prob. 5AYLO
Ch. 18.1 - Prob. 6AYLOCh. 18.1 - Prob. 7AYLOCh. 18.2 - Describe the size, shapte, and contents of an...Ch. 18.2 - Prob. 7BYGOCh. 18.2 - Prob. 8BYGOCh. 18.2 - Prob. 9BYGOCh. 18.2 - Prob. 10BYGOCh. 18.2 - Prob. 11BYGOCh. 18.2 - Prob. 12BYGOCh. 18.2 - Prob. 1AYLOCh. 18.2 - Prob. 2AYLOCh. 18.2 - Prob. 3AYLOCh. 18.2 - Three ways of quantifying the RBCs and hemoglobin...Ch. 18.2 - Prob. 5AYLOCh. 18.2 - Prob. 6AYLOCh. 18.2 - Prob. 7AYLOCh. 18.2 - Prob. 8AYLOCh. 18.2 - Prob. 9AYLOCh. 18.2 - Prob. 10AYLOCh. 18.2 - Causes and effects of hemoglobin deficiencies and...Ch. 18.3 - Prob. 13BYGOCh. 18.3 - Prob. 14BYGOCh. 18.3 - Prob. 15BYGOCh. 18.3 - Prob. 16BYGOCh. 18.3 - Prob. 1AYLOCh. 18.3 - Prob. 2AYLOCh. 18.3 - Prob. 3AYLOCh. 18.3 - Prob. 4AYLOCh. 18.3 - Prob. 5AYLOCh. 18.3 - Prob. 6AYLOCh. 18.3 - Hemolytic disease of the newborn; why it seldom...Ch. 18.4 - Prob. 17BYGOCh. 18.4 - Prob. 18BYGOCh. 18.4 - Prob. 19BYGOCh. 18.4 - Prob. 20BYGOCh. 18.4 - Prob. 21BYGOCh. 18.4 - Prob. 1AYLOCh. 18.4 - Prob. 2AYLOCh. 18.4 - Prob. 3AYLOCh. 18.4 - Prob. 4AYLOCh. 18.4 - Prob. 5AYLOCh. 18.4 - Prob. 6AYLOCh. 18.4 - Prob. 7AYLOCh. 18.5 - Prob. 22BYGOCh. 18.5 - Prob. 23BYGOCh. 18.5 - Prob. 24BYGOCh. 18.5 - Prob. 25BYGOCh. 18.5 - Prob. 26BYGOCh. 18.5 - Prob. 1AYLOCh. 18.5 - Prob. 2AYLOCh. 18.5 - Prob. 3AYLOCh. 18.5 - Prob. 4AYLOCh. 18.5 - Prob. 5AYLOCh. 18.5 - Prob. 6AYLOCh. 18.5 - Prob. 7AYLOCh. 18.5 - Prob. 8AYLOCh. 18.5 - Prob. 9AYLOCh. 18.5 - Prob. 10AYLOCh. 18.5 - Prob. 11AYLOCh. 18.5 - Terms for unwanted or inappropriate clotting in a...Ch. 18.5 - Prob. 13AYLOCh. 18 - Antibodies belong to a class of plasma proteins...Ch. 18 - Prob. 2TYRCh. 18 - Prob. 3TYRCh. 18 - Prob. 4TYRCh. 18 - Prob. 5TYRCh. 18 - Prob. 6TYRCh. 18 - Prob. 7TYRCh. 18 - Prob. 8TYRCh. 18 - Prob. 9TYRCh. 18 - Prob. 10TYRCh. 18 - Prob. 11TYRCh. 18 - Prob. 12TYRCh. 18 - Prob. 13TYRCh. 18 - Prob. 14TYRCh. 18 - Prob. 15TYRCh. 18 - Prob. 16TYRCh. 18 - Prob. 17TYRCh. 18 - Prob. 18TYRCh. 18 - Prob. 19TYRCh. 18 - Prob. 20TYRCh. 18 - Prob. 1BYMVCh. 18 - Prob. 2BYMVCh. 18 - Prob. 3BYMVCh. 18 - Prob. 4BYMVCh. 18 - Prob. 5BYMVCh. 18 - Prob. 6BYMVCh. 18 - Prob. 7BYMVCh. 18 - Prob. 8BYMVCh. 18 - Prob. 9BYMVCh. 18 - Prob. 10BYMVCh. 18 - Prob. 1WWTSCh. 18 - Prob. 2WWTSCh. 18 - Prob. 3WWTSCh. 18 - Prob. 4WWTSCh. 18 - Prob. 5WWTSCh. 18 - Prob. 6WWTSCh. 18 - Prob. 7WWTSCh. 18 - All formed elements of the blood except platelets...Ch. 18 - When RBCs die and break down, the globin moiety of...Ch. 18 - Prob. 10WWTSCh. 18 - Prob. 1TYCCh. 18 - Prob. 2TYCCh. 18 - Prob. 3TYCCh. 18 - Prob. 4TYCCh. 18 - Prob. 5TYC
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