For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained Concept introduction: Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine The requirement of an odd number of electron pair is called Huckel’s rule . A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic. Each π bond count as two π electron and lone pair also count as two π electron

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Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 18, Problem 61IP

Interpretation Introduction

Interpretation: For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained

Concept introduction:

Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property

Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine

The requirement of an odd number of electron pair is called Huckel’s rule. A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic.

Each π bond count as two π electron and lone pair also count as two π electron

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Answer 2

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Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 18, Problem 61IP

Interpretation Introduction

Interpretation: For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained

Concept introduction:

Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property

Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine

The requirement of an odd number of electron pair is called Huckel’s rule. A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic.

Each π bond count as two π electron and lone pair also count as two π electron

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 3

Question

Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 18, Problem 61IP

Interpretation Introduction

Interpretation: For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained

Concept introduction:

Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property

Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine

The requirement of an odd number of electron pair is called Huckel’s rule. A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic.

Each π bond count as two π electron and lone pair also count as two π electron

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 18, Problem 61IP

Interpretation Introduction