Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 18, Problem 4PDQ
Consider the CT/CGRP example of alternative splicing shown in Figure 18.3. Which different types of alternative splicing patterns are represented?
FIGURE 18.3 Alternative splicing of the CT/JCGRP gene transcript. The primary transcript, which is shown in the middle of the diagram, can be spliced into two different mRNAs, both containing the first three exons but differing in their final exons.
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Please answer q3
Respond to the following in a minimum of 175 words:
How might CRISPR-Cas 9 be used in research or, eventually, therapeutically in patients?
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Do the advantages of using this technology outweigh the disadvantages (or vice versa)? Explain your position.
You are studying the effect of directional selection on body height in three
populations (graphs a, b, and c below).
(a) What is the selection differential? Show your calculation. (2 pts)
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Explain your answer. (2 pts)
(c) If you examined the offspring in the next generation in each population,
which population would have the highest mean height? Why? (2 pts)
(a)
Midoffspring height (average height of offspring)
Short
Short
Short
Short
(c)
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(b)
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Tall
Short
Tall
Short
Short
Tall
Midparent height
(average height of
Mean of population = 65 inches
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Mean of population = 65 inches
Mean of breading parents = 70 inches
Mean of population = 65 inches
Mean of breading parents = 70 inches
Chapter 18 Solutions
Concepts of Genetics (12th Edition)
Ch. 18 - Some mutations in the tra gene of Drosophila cause...Ch. 18 - Some scientists use the analogy that the...Ch. 18 - Consider the example that actin mRNA localization...Ch. 18 - What is alternative splicing, where does it occur,...Ch. 18 - What role might the expanded tri- and...Ch. 18 - DM1 is characterized by a phenomenon known as...Ch. 18 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 18 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 18 - List three types of alternative splicing patterns...Ch. 18 - Consider the CT/CGRP example of alternative...
Ch. 18 - Explain how the use of alternative promoters and...Ch. 18 - Explain how a tissue-specific RNA-binding protein...Ch. 18 - The regulation of mRNA decay relies heavily upon...Ch. 18 - Nonsense-mediated decay is an mRNA surveillance...Ch. 18 - AU-rich elements (AREs) are cis-elements in mRNAs...Ch. 18 - What are processing bodies (P bodies), and what...Ch. 18 - In 1998, future Nobel laureates Andrew Fire and...Ch. 18 - Present an overview of RNA interference (RNAi)....Ch. 18 - RNAi may be directed by small interfering RNAs...Ch. 18 - Prob. 14PDQCh. 18 - In principle, RNAi may be used to fight viral...Ch. 18 - Prob. 16PDQCh. 18 - Prob. 17PDQCh. 18 - Prob. 18PDQCh. 18 - Prob. 19PDQCh. 18 - How is it possible that a given mRNA in a cell is...Ch. 18 - Prob. 21PDQCh. 18 - Prob. 22PDQCh. 18 - Prob. 23PDQCh. 18 - Prob. 24ESPCh. 18 - Prob. 25ESPCh. 18 - Mutations in the low-density lipoprotein receptor...Ch. 18 - RNA helicases are a class of proteins that bind...Ch. 18 - While miRNA response elements (MREs) may be...Ch. 18 - RNAi is currently being tested as a therapeutic...Ch. 18 - The localization and translational control of...Ch. 18 - Explain how the expression of a single gene can be...
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