Human Biology: Concepts and Current Issues
Human Biology: Concepts and Current Issues
7th Edition
ISBN: 9780321821652
Author: Michael D. Johnson
Publisher: Benjamin Cummings
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Chapter 18, Problem 3QC
Summary Introduction

To review:

The action a person should take with a mutated BRCA (breast cancer gene) gene.

Introduction:

Mutation refers to the change within the structure of the gene by addition, deletion, or alteration of other kinds. Mutation can lead to the formation of tumors in the body. Tumors are cells that divide uncontrollably. They become cancerous when they start invading other organs. This is when it becomes difficult to treat cancers. The most common type of cancers is of the lungs, liver, breasts, thyroid, prostate, and skin.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY