HUMAN A&P LL W/MOD.MAST.TCC ACCESS >IB<
HUMAN A&P LL W/MOD.MAST.TCC ACCESS >IB<
11th Edition
ISBN: 9781323847572
Author: Marieb
Publisher: Pearson Custom Publishing
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Chapter 18, Problem 3CCS

54-Year-Old Female with a Defective Heart Valve

Dr. El-Sheikh is a 54-year-old Egyptian female who complains of weakness, fatigue, shortness of breath, chest pain, and dizziness. Her heart rate is 96 beats/min, and her blood pressure is 148/54 mm Hg. You notice that she nods her head with every heartbeat, and her radial pulse is very strong and abrupt. Her heart sounds are abnormal, with a long diastolic murmur at the right sternal margin in the second intercostal space.

Chapter 18, Problem 3CCS, 54-Year-Old Female with a Defective Heart Valve Dr. El-Sheikh is a 54-year-old Egyptian female who

Her doctor orders an echocardiogram, which shows that Dr. El-Sheikh has severe aortic regurgitation (backflow of blood through an incompetent valve) and an enlarged left ventricle.

3. Why is Dr. El-Sheikh’s systolic blood pressure abnormally high and her diastolic blood pressure abnormally low?

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

Chapter 18 Solutions

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