Chapter 18, Problem 37P

Interpretation Introduction

Interpretation:

The starting material that led to the indicated product through the given defined reactions is to be deduced.

Concept Introduction:

▸ LDA is lithium disopyramide. It is a strong base.

▸ In ${\text{S}}_{\text{N}}\text{2}$ reaction, one bond is broken and one bond is formed. In ${\text{S}}_{\text{N}}\text{2}$ reaction, the nucleophile attacks the carbon with less steric hindrance.

▸ Alkylation of the ketone takes place with the help of lithium enolates.

▸ Sodium hydride is used to generate the enolate ions.

▸ The electrophilic substitution reaction is the type of reaction in which an electrophile displaces hydrogen from the compound.