Concept explainers
Interpretation:
The reaction sequence of the given compounds along with the reagents are to be determined.
Concept Introduction:
Electrophiles are electron deficient species which has positive or partially positive charge. Lewis acids are electrophiles which accept electron pair.
Nucleophiles are electron rich species which has negative or partially negative charge. Lewis bases are nucleophiles which donate electron pair.
Alkylation of the
LDA stands for lithium disopyramide. It is a strong base.
In
Sn2 is a kind of nucleophilic substitution reaction mechanism. Since two reacting species are involved in the slow (rate-determing) step, this leads to the term substitution nucleophilic (bi-molecular) or
In
When halogen substitution reaction takes place in the presence of acid, it is called acid catalyzed halogenation reaction.
Decarboxylation is the chemical reaction which transfers
Alkylation of ketones takes place with the help of lithium enolates.
Sodium hydride is used to generate the enolate ions.
The
When halogen substitution reaction takes places in the presence of acid, it is called acid catalyzed halogenation reaction.
When halogen substitution reaction takes places in the presence of a base, it is called base prompted halogenation reaction.
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