Lehninger Principles of Biochemistry (Instructor's)
Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 18, Problem 15P
Summary Introduction

To suggest: A mechanism for the reaction which is based on the mechanism in Figure 18-6. The reaction involves threonine elimination at β-carbon.

Introduction:

Threonine dehydrogenase is the enzyme which is responsible for the breakdown of threonine. This enzyme also catalyzes the conversion of threonine to α-ketobutyrate and ammonia. The PLP or pyridoxal phosphate acts as the cofactor in the conversion of threonine to α-ketobutyrate and ammonia.

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