Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
12th Edition
ISBN: 9780134811390
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 18, Problem 13PDQ
RNAi may be directed by small interfering RNAs (siRNAs) or microRNAs (miRNAs); how are these similar, and how are they different?
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Chapter 18 Solutions
Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
Ch. 18 - Some mutations in the tra gene of Drosophila cause...Ch. 18 - Some scientists use the analogy that the...Ch. 18 - Consider the example that actin mRNA localization...Ch. 18 - What is alternative splicing, where does it occur,...Ch. 18 - What role might the expanded tri- and...Ch. 18 - DM1 is characterized by a phenomenon known as...Ch. 18 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 18 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 18 - List three types of alternative splicing patterns...Ch. 18 - Consider the CT/CGRP example of alternative...
Ch. 18 - Explain how the use of alternative promoters and...Ch. 18 - Explain how a tissue-specific RNA-binding protein...Ch. 18 - The regulation of mRNA decay relies heavily upon...Ch. 18 - Nonsense-mediated decay is an mRNA surveillance...Ch. 18 - AU-rich elements (AREs) are cis-elements in mRNAs...Ch. 18 - What are processing bodies (P bodies), and what...Ch. 18 - In 1998, future Nobel laureates Andrew Fire and...Ch. 18 - Present an overview of RNA interference (RNAi)....Ch. 18 - RNAi may be directed by small interfering RNAs...Ch. 18 - Prob. 14PDQCh. 18 - In principle, RNAi may be used to fight viral...Ch. 18 - Prob. 16PDQCh. 18 - Prob. 17PDQCh. 18 - Prob. 18PDQCh. 18 - Prob. 19PDQCh. 18 - How is it possible that a given mRNA in a cell is...Ch. 18 - Prob. 21PDQCh. 18 - Prob. 22PDQCh. 18 - Prob. 23PDQCh. 18 - Prob. 24ESPCh. 18 - Prob. 25ESPCh. 18 - Mutations in the low-density lipoprotein receptor...Ch. 18 - RNA helicases are a class of proteins that bind...Ch. 18 - While miRNA response elements (MREs) may be...Ch. 18 - RNAi is currently being tested as a therapeutic...Ch. 18 - The localization and translational control of...Ch. 18 - Explain how the expression of a single gene can be...
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- The number of microRNAs encoded by the genome varies widely among organisms: some species have many miRNA genes and other species have relatively few. Researchers have determined the number of miRNA genes possessed by different species and have made the following observations: Q. The number of miRNA genes found on a chromosome is not correlated with chromosome length. In other words, longer chromosomes do not necessarily have more miRNA genes.arrow_forwardWhat is the origin of small interfering RNAs, microRNAs, and Piwi-interacting RNAs? What do these RNA molecules do in the cell?arrow_forwardDescribe the synthesis of prokaryotic RNA in brief. What are small non coding RNAs or microRNAs and SiRNAs? Describe the inbitory mechanism of gene expression by SiRNAs in brief.arrow_forward
- What is RNA modification? Explain with the help of diagramsarrow_forwardHow do miRNAs and siRNAs target RNAs for destruction?arrow_forwardThe RNAi and the microRNA (miRNA) pathways share many components and characteristics. What unique feature distinguishes the microRNA pathway from RNAi? a) only the RNAi pathway is initiated by dsRNA molecules b) the miRNA pathway does not require Dicer c) the miRNA pathway does not require RISC. d) miRNAs have 100% complementarity with their mRNA targets to block translation e) siRNAs that act in RNAi have 100% complementarity with their mRNA targets resulting in endonucleolytic cleavagearrow_forward
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