Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 17.5, Problem 2CC
MAKE CONNECTIONS → Individuals heterozygous for the sickle-cell allele are generally healthy but show
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Q11. One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here:
https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451
Please navigate to the link above and ensure that you click to reveal the transcript table. Then use the information in the table to answer the following question.
What is the NCBI accession number (including the version) of the RefSeq Match for the first transcript (CACNA1S-201)?
Answer: NCBI accession number (including the version) of the RefSeq Match for the first transcript (CACNA1S-201) is ...
5
Q17. In a dog breed, a gene B coding for fur color has a dominant allele B for black fur. Gene B has a recessive
allele b that produces brown fur. A second gene I, has a dominant allele I that is epistatic to the color locus and
can inhibit pigment formation. Gene I has a recessive allele, i, on that permits pigment deposition in the fur.
Note: the inhibition of pigment formation by the epistatic allele I causes the fur to be white.
A) What is the phenotype of the individuals with the below genotypes?
bbii
Bbli
Bbii
bbli
BBIi
B) What are the phenotypes and genotypes of the offspring of each of these dog crosses?
a. bbii x Bbli
b. bbii x Bbii
c. bbli x BBli
C) What type of epistasis is described in this problem?
English (United States)
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Chapter 17 Solutions
Campbell Biology (11th Edition)
Ch. 17.1 - Prob. 1CCCh. 17.1 - What polypeptide product would you expect from a...Ch. 17.1 - Prob. 3CCCh. 17.2 - MAKE CONNECTIONS In a research artide about...Ch. 17.2 - What enables RNA polymerase to start transcribing...Ch. 17.2 - WHAT IF? Suppose X-rays caused a sequence change...Ch. 17.3 - There are about 20,000 human protein-coding genes....Ch. 17.3 - How is RNA splicing similar to how you would watch...Ch. 17.3 - Prob. 3CCCh. 17.4 - What two processes ensure that the correct amino...
Ch. 17.4 - Prob. 2CCCh. 17.4 - Prob. 3CCCh. 17.4 - WH AT IF? In eukaryotic cells, mRNAs have been...Ch. 17.5 - What happens when one nucleotide pair is lost from...Ch. 17.5 - MAKE CONNECTIONS Individuals heterozygous for the...Ch. 17.5 - WHAT IF? DRAW IT The template strand of a gene...Ch. 17 - Describe the process of gene expression, by which...Ch. 17 - What are the similarities and differences in the...Ch. 17 - What function do the 5' cap and the poly-A tail...Ch. 17 - Prob. 17.4CRCh. 17 - What will be the results of chemically modifying...Ch. 17 - In eukaryotic cells, transcription cannot begin...Ch. 17 - Which of the following is not true of a codon? (A)...Ch. 17 - The anticodon of a particular tRNA molecule is (A)...Ch. 17 - Which of the following is not true of RNA...Ch. 17 - Which component is not directly involved in...Ch. 17 - Using Figure 17.6, identify a 5' 3' sequence of...Ch. 17 - Prob. 7TYUCh. 17 - Would the coupling of the processes shown in...Ch. 17 - Prob. 9TYUCh. 17 - Prob. 10TYUCh. 17 - scientific inquiry Knowing that the genetic code...Ch. 17 - Prob. 12TYUCh. 17 - Prob. 13TYU
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Think Critically. Provide a concise explanation of your answer. A mutation on an autosome causes a particular protein to be overproduced, and the excess protein accumulates in the liver and damages it. Would the resulting disorder most likely be inherited in an autosomal dominant or recessive pattern? Expression of the SYR gene on the Y chromosome gives rise to the male phenotype in humans. What do you think the inheritance pattern of SYR alleles is called? 22q11.2 deletion syndrome, also called DiGeorge syndrome, causes atypical parathyroid glands, a heart defect, and an underdeveloped thymus gland. About 85% of patients have a microdeletion of part of chromosome 22. A girl, her mother, and a maternal aunt have very mild DiGeorge syndrome. They all have a reciprocal translocation of chromosomes 22 and 2. How can a microdeletion and a translocation cause the same symptoms? Why were the people with the translocation less severely affected than the people with microdeletion? What other…arrow_forwardDiscuss Concepts Many human diseases are caused by recessive alleles that are not expressed in heterozygotes. Some people think that eugenicsthe selective breeding of humans to eliminate undesirable genetic traitsprovides a way for us to rid our populations of such harmful alleles. Explain why eugenics cannot eliminate such genetic traits from human populations.arrow_forward4e. You also study the expression of 3 different mutants for this gene. For each mutant answer the following: Does this mutation change the sequence of the protein produced? Why or why not? If it does change the sequence of protein be sure to write out the new sequence. If it does not change the protein sequence, what effect (if any) would you expect it to have on expression of the gene? 1 20 ORI 40 60 5'..TTCGAGCTCTCGTCGTCGAGATACGCGATGATATTACTGGTAATATGGGGATGCACTATC...3’ 3'...AAGCTCGAGAGCAGCAGCTCTATGCGCTACTATAATGACCATTATACCCCTACGTGATAG...5’ promoter i. Mutant A has a single base pair substitution with the T/A being replaced with C/G base pair at position 35 (position denoted by the * in the sequence above). ii. Mutant B has a 2 G/C pairs inserted between position 19 and 20 (position denoted by the ^ in the sequence above).arrow_forward
- help.arrow_forwardPlease help me. Thanksarrow_forwardEC4. In a test-cross of trihybrid drosophila the following phenotypes and number of offspring were found. Without doing any calculations, answer the following questions: +++ 669 abc 653 ++c 121 ab+ 139 +b+ 2280 a+c 2215 +bc 3 a++ 2 a) What were the genotypes of the parental strains? (fill in) b). What is the gene order?arrow_forward
- Neep help ASAP. A red flowered plant was crossed with a blue flowered plant and produced all purple flowered plants. When the purple flowered plants were crossed with each other they produced 5 red plants, 5 blue plants, 20 deep purple plants, 20 light lilac plants, and 30 purple plants How many genes are involved in the color production? Assume that red color is caused by an A allele and blue color by a B allele and determine the likely genotype of the plants in the F2 generation.arrow_forwardI do not understand.arrow_forward>mutant1…arrow_forward
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