Chapter 17, Problem 9PDQ

Summary Introduction

To explain: The purpose of ATP hydrolysis required for chromatin modeling by the SWI/SNF complex.

Introduction: The tight association of DNA with histones and other chromatin-binding proteins restricts the access of DNA for proteins involved in many functions like transcription. This restrictive conformation is called closed chromatin. The structure of chromatin must become open to initiate the transcription by RNA polymerase. This process is called chromatin alteration or chromatin remodeling.