Type IV hypersensitivity is also known as delayed-type hypersensitivity. It is different from the other three types because it is not antibody mediated, rather it is cell-mediated hypersensitivity. It is a delayed type because it can take 1-3 days of time to respond after the antigen exposure. Delayed-type hypersensitivity skin reactions are also called allergic contact dermatitis in which small molecules or haptens penetrates into the skin activating effector T cells and cause tissue damage, resulting in irritation, rashes, and blisters.

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Chapter 17, Problem 5MC

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Type IV hypersensitivity is also known as delayed-type hypersensitivity. It is different from the other three types because it is not antibody mediated, rather it is cell-mediated hypersensitivity. It is a delayed type because it can take 1-3 days of time to respond after the antigen exposure. Delayed-type hypersensitivity skin reactions are also called allergic contact dermatitis in which small molecules or haptens penetrates into the skin activating effector T cells and cause tissue damage, resulting in irritation, rashes, and blisters.

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