Anatomy and Physiology by OpenStax
17th Edition
ISBN: 9781506698021
Author: J. Gordon Betts;Dean H. Kruse;Kelly A. Young;Peter DeSaix;Brandon Poe;Oksana Korol;James A. Wise;Eddie Johnson;Jody E. Johnson;Mark Womble
Publisher: XANEDU PUBLISHING
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Chapter 17, Problem 56CTQ
What would be the physiological consequence of a disease that destroyed the beta cells of the pancreas?
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 17 Solutions
Anatomy and Physiology by OpenStax
Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Endocrine glands ________. secrete hormones that...Ch. 17 - Chemical signaling that affects neighboring cells...Ch. 17 - A newly developed pesticide has been observed to...Ch. 17 - A small molecule binds to a G protein, preventing...Ch. 17 - A student is in a car accident, and although not...
Ch. 17 - The hypothalamus is functionally and anatomically...Ch. 17 - Which of the following is an anterior pituitary...Ch. 17 - How many hormones are produced by the posterior...Ch. 17 - Which of the following hormones contributes to the...Ch. 17 - Which of the following statements about the...Ch. 17 - The secretion of thyroid hormones is controlled by...Ch. 17 - The development of a goiter indicates that...Ch. 17 - Iodide ions cross from the bloodstream into...Ch. 17 - When blood calcium levels are low, PTH stimulates...Ch. 17 - Which of the following can result from...Ch. 17 - The adrenal glands are attached superiorly to...Ch. 17 - What secretory cell type is found in the adrenal...Ch. 17 - Cushings disease is a disorder caused by ________....Ch. 17 - Which of the following responses s not part of the...Ch. 17 - What cells secrete melatonin? melanocytes...Ch. 17 - The production of melatonin is inhibited by...Ch. 17 - The gonads produce what class of hormones? amine...Ch. 17 - The production of FSH by the anterior pituitary is...Ch. 17 - The function of the placental hormone human...Ch. 17 - If an autoimmune disorder targets the alpha cells,...Ch. 17 - Which of the following statements about insulin is...Ch. 17 - The walls of the atria produce which hoimone?...Ch. 17 - The end result of the RAAS is to ________. reduce...Ch. 17 - Athletes may take synthetic EPO to boost their...Ch. 17 - Hormones produced by the thymus play a role in the...Ch. 17 - The anterior pituitary gland develops from which...Ch. 17 - In the elderly, decreased thyroid function causes...Ch. 17 - Describe several main differences in the...Ch. 17 - Compare and contrast endocrine and exocrine...Ch. 17 - True or false: Neurotransmitters are a special...Ch. 17 - Compare and contrast the signaling events involved...Ch. 17 - Describe the mechanism of hormone response...Ch. 17 - Compare and contrast the anatomical relationship...Ch. 17 - Name the target tissues for prolactin.Ch. 17 - Explain why maternal iodine deficiency might lead...Ch. 17 - Define hyperthyroidism and explain why one of its...Ch. 17 - Describe the role of negative feedback in the...Ch. 17 - Explain why someone with a parathyroid gland tumor...Ch. 17 - What are the three regions of the adrenal cortex...Ch. 17 - If innervation to the adrenal medulla were...Ch. 17 - Compare and contrast the short-term and long-term...Ch. 17 - Seasonal affective disorder (SAD) is a mood...Ch. 17 - Retinitis pigmentosa (RP) is a disease that causes...Ch. 17 - Compare and contrast the role of estrogens and...Ch. 17 - Describe the role of placental secretion of...Ch. 17 - What would be the physiological consequence of a...Ch. 17 - Why is foot care extremely important for people...Ch. 17 - Summarize the role of GI tract hormones following...Ch. 17 - Compare and contrast the thymus gland in infancy...Ch. 17 - Distinguish between the effects of menopause and...
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