Organic Chemistry
Organic Chemistry
3rd Edition
ISBN: 9781119338352
Author: Klein
Publisher: WILEY
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Chapter 17, Problem 50IP
Interpretation Introduction

Interpretation: For the given transformation an efficient synthesis should be proposed.

Concept introduction:

  • When approaching a synthesis problem two questions should be asked
    1. 1.  Is there a change in the carbon skeleton?
    2. 2. Is there a change in the position or identity of the functional group
  • When approaching a synthesis problem, should not encounter a one-step method
  • The desired transformation can achieve in two steps
  • There are two ways to introduce functionality at a benzylic position
    1. 1. Oxidation, which produces benzoic acid at benzylic position
    2. 2. Radical bromination, which produces benzylic halide.

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Organic Chemistry

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