Biochemistry, The Molecular Basis of Life, 6th Edition
Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 17, Problem 2Q
Summary Introduction

To review:

The effect of the given compounds/conditions on the structure of deoxyribonucleic acid (DNA):

a. Ethanol

b. Heat

c. Dimethylsulfate

d. Nitrous acid

e. 5-Bromouracil (5-BU)

Introduction:

The DNAis prone to mutations, thatis, permanent structural changes in DNA caused by deletion, duplication, and rearrangement of its base pairs. Mutations can also be caused by a mismatch of the base pairs. There are many factors thatcan cause mutations, these are called mutagens.

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Biochemistry, The Molecular Basis of Life, 6th Edition

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