Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 17, Problem 17.4CR
Summary Introduction

To explain: The function of tRNAs in building polypeptides in the context of the ribosome.

Introduction:

DNA contains genetic information which is encoded in nucleotide base sequences. These sequences are transcribed into mRNA codons and are then translated into polypeptides by tRNA molecules in the ribosome. During translation, the codon of the mRNA sequence is paired with its complementary anticodon of the tRNA, and the codon-specific amino acid is delivered to the other end of the tRNA. The amino acids are then linked together to form the polypeptide chain.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

Chapter 17 Solutions

Campbell Biology

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