Campbell Biology (10th Edition)
Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 17, Problem 17.1CR

Describe the process of gene expression, by which a gene affects the phenotype of an organism.

Expert Solution & Answer
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Summary Introduction

To review: Gene expression affects the phenotype of an organism.

Concept introduction:

DNA is known as the blueprint of life as it controls gene expression. The genetic information of DNA is based on the nucleotide base sequences. These sequences are transcribed into mRNA triplets and are called codons. These mRNA triplet nucleotides are translated into polypeptide chains which code for specific proteins and enzymes. This is known as gene expression.

Explanation of Solution

DNA consists of genetic instructions in the form of gene sequences. It directs messenger RNA (mRNA) synthesis in the cell. During the formation of mRNA in a process which is known as transcription, each letter in the gene sequence is copied which codes for a particular amino acid. The polypeptide chain is synthesized on the basis of amino acid sequences in the reading frame. This process is known as translation. Specific proteins also known as functional gene products control the phenotypic traits in an individual such as eye color, hair color etc. These traits may also be controlled by cumulative action of many proteins.

Functional gene products are formed as a result of gene expression. There may be variation in the expression of the genes. Some genes are dominant over others which influence the appearance of the trait. For example, parents with blue eyes can have a child with brown eyes. This is because brown eye color trait is dominant over blue eye color.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

Chapter 17 Solutions

Campbell Biology (10th Edition)

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QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY