ORGANIC CHEMISTRY - LOOSELEAF W/CONNECT
ORGANIC CHEMISTRY - LOOSELEAF W/CONNECT
6th Edition
ISBN: 9781266060144
Author: SMITH
Publisher: MCG
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Chapter 16.5, Problem 11P
Interpretation Introduction

Interpretation: The stepwise mechanism for the intramolecular Friedel–Crafts acylation of compound A to form B is to be drawn.

Concept introduction: The Friedel-Craft acylation is a type of electrophilic substitution reaction. AlCl3 is used as Lewis acid which ionizes the carbon-halogen bond of the acid chloride and forms a positively charged carbon electrophile which is resonance stabilized. Then the electrophile reacts with benzene.

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ORGANIC CHEMISTRY - LOOSELEAF W/CONNECT

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