Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 16.3, Problem 2C
Summary Introduction
Concept introduction: Inheritance patterns explain the transmission of a trait in families. They are classified as autosomal or X-linked and dominant or recessive. Based on this, inheritance patterns are autosomal dominant and recessive, and X-linked dominant and recessive.
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2. STATEMENT:
A woman and man both do not have sickle-cell anemia, but both had one parent who
had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait.
a) What is the genotype for the woman, man and each of their parents?
b) This couple unexpectedly is going to have their first child.
i.
What's the probability that their child will have not have sickle cell like the couple?
ii.
What's the probability that the child will have sickle cell like one the grandparents?
Which of the following genetic diseases is/are inherited as an autosomal dominant trait: sickle cell anemia, hemophilia A, Huntington’s disease?
3) State whether each of the following genetic defects is inherited as an autosomal recessive, autosomal dominant, or X-linked recessive trait: phenylketonuria (PKU), sickle cell anemia, cystic fibrosis, Tay-Sachs disease, Huntington’s disease, and hemophilia A.
Chapter 16 Solutions
Biology (MindTap Course List)
Ch. 16.1 - Distinguish between karyotyping and pedigree...Ch. 16.1 - Prob. 2LOCh. 16.1 - Prob. 3LOCh. 16.1 - Prob. 1CCh. 16.1 - Prob. 2CCh. 16.1 - Describe two ways in which genome database...Ch. 16.1 - Prob. 4CCh. 16.2 - Explain how nondisjunction in meiosis is...Ch. 16.2 - Distinguish among the following structural...Ch. 16.2 - Prob. 6LO
Ch. 16.2 - VISUALIZE Draw a simple sketch illustrating how...Ch. 16.2 - Prob. 2CCh. 16.2 - Prob. 3CCh. 16.2 - Prob. 4CCh. 16.3 - State whether each of the following genetic...Ch. 16.3 - Which of the following genetic diseases is/are...Ch. 16.3 - Prob. 2CCh. 16.3 - Prob. 3CCh. 16.4 - Briefly discuss the process of gene therapy,...Ch. 16.4 - Prob. 1CCh. 16.5 - State the relative advantages and disadvantages of...Ch. 16.5 - Distinguish between genetic screening programs for...Ch. 16.5 - Prob. 1CCh. 16.5 - Prob. 2CCh. 16.6 - Prob. 11LOCh. 16.6 - Prob. 1CCh. 16.6 - CONNECT To be expressed, an autosomal recessive...Ch. 16.6 - Prob. 3CCh. 16 - Prob. 1TYUCh. 16 - An abnormality in which there is one more or one...Ch. 16 - The failure of chromosomes to separate normally...Ch. 16 - Prob. 4TYUCh. 16 - Prob. 5TYUCh. 16 - Prob. 6TYUCh. 16 - Prob. 7TYUCh. 16 - Prob. 8TYUCh. 16 - Examine the following pedigrees. Which is the most...Ch. 16 - Examine the following pedigrees. Which is the most...Ch. 16 - Prob. 11TYUCh. 16 - SCIENCE, TECHNOLOGY, AND SOCIETY Imagine that you...Ch. 16 - A common belief about human genetics is that an...Ch. 16 - Prob. 14TYUCh. 16 - EVOLUTION LINK Explain some of the evolutionary...
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- Describe the genetics of Huntington's Disease (choose all that are correct): X-linked Disease-causing alleles are full or partial loss-of-function alleles Autosomal Dominant Rare Late age of onset Recessivearrow_forwardAaBbCcDc AaBbCcD Ac Heading 1 Heading 2 Title Subtitle Subtle Em.. Emphasis Intense E... Strong Quote Int Paragraph Styles 4 Genetic Inheritance Patterns Retinitis pigmentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently the dominant forms are often less severe. Eric's form of RP is Usher's Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective carried on one of the chromosomes that determines sex. Usher's Type II is recessive, so for Eric this means that both his Mom and Dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. gene from your Mom and one from your Dad). Autosomal means it is not Question below short answer approach image you are the genetics counselor, should Eric have children? Imagine he has a daughter (he has two, but both are adopted). What advice would you give Eric if his wife was a carrier from a genetics counseling viewpoint? Describe all the possibilities,…arrow_forwardGenetic disorders Complete the following statements to describe several genetic disorders and their symptoms. Choices can be used more than once. The disorder called causes blue-colored skin, sickle-cell disease osteogenesis imperfecta The disorder called that leads to weakened, brittle bones. causes defective collagen methemoglobinemia autosomal dominant The disorder called causes abnormally thick mucus in the bronchial tubes and pancreatic ducts. autosomal recessive The disorder called leads to progressive cystic fibrosis degeneration of neurons in the brain. alkaptonuria The disorder called causes urine to be black. Huntington disease acer %23 24 & 4 8. 9. e y u < 6arrow_forward
- Huntington disease (HD) is a genetic disorder that usually first appears in middle age and, over time, leads to involuntary movements, impaired speech, difficulty swallowing and speaking, and cognitive decline. There is no cure for HD, and affected individuals eventually die, usually after 10 to 15 years of progressively worsening symptoms. Huntington disease is inherited as an autosomal dominant disorder. Presymptomatic genetic testing for HD is available for people with a family history of the disease. Individuals who have a parent with HD have a 50% chance of inheriting the HD gene and eventually having HD. Some of these individuals want to know if they will eventually get the disease, and they undergo presymptomatic genetic testing. Others do not want to know, given that there is no cure or effective treatment for the disease. If you were at risk for HD, would you want to undergo genetic testing? What are some reasons for and against having a genetic test for HD?arrow_forwardWhat is a monogenic disease?arrow_forwarda. A man who does not have Huntington’s Disease has children with a woman with Huntington’s Disease whose mother did not have Huntington’s Disease. What proportion of their children would be expected to have Huntington’s Disease b.A man who does have Huntington’s Disease and a woman who does not have Huntington’s Disease have a child who does not have Huntington’s Disease. What is the man’s genotype c.A man who does have Huntington’s Disease and a woman who does not have Huntington’s Disease have eight children, all of whom have Huntington’s Disease. Can you be certain of the man’s genotype? Why or why not? What genotype is MOST likely and whyarrow_forward
- What is the most likely mode of inheritance for the disease depicted in the following pedigree? I II III 1 1 2 1 2 autosomal recessive autosomal dominant 3 3 2 4 4 5 5 6arrow_forwardRecessive genetic disorders are more frequent than disorders inherited as dominant because : a) recessive genetic disorders are limited to persons of the same ethnicity c) dominant genetic disorders are never expressed in males d) people carrying dominant genetic disorders always die before birth e ) carriers are not eliminated by the disease before reproductionarrow_forwardWhat is the recurrence risk for autosomal dominant inheritance and recessive inheritance?arrow_forward
- What is the frequency of sickle cell disease (anemia)? https://ghr.nlm.nih.gov/condition/sickle-cell-disease#inheritance https://www.cdc.gov/ncbddd/sicklecell/traits.htmlarrow_forwardPlssssssss helppppp, What are the symptoms of Down syndrome and what is the long term prognosis is for the person who has this disorder?arrow_forward20arrow_forward
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