A blood lead level of 70 mg/ml has been commonly accepted as safe. However, researchers have noted that some neurophysiological symptoms of lead poisoning appear in people whose blood lead levels are below 70 mg/ml. The article “Subclinical Neuropathy at Safe Levels of Lead Exposure” (Archives of Environmental Health [1975]: 180–183) gave the following nerve-conduction velocities for a group of workers who were exposed to lead in the workplace but whose blood lead levels were below 70 mg/ml and for a group of controls who had no exposure to lead:
Use a level 0.05 rank-sum test to determine whether there is a significant difference in
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Introduction To Statistics And Data Analysis
- 1. Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying tables (based on data from "Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme," by MacGregor et al., British Medical Journal, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril is effective in lowering systolic blood pressure? Subject Before (x) 200 After (y) А В C D E F G H I K 174 198 170 179 182 193 209 185 155 169 210 191 170 177 167 159 151 176 183 159 145 146 177 2. A study was conducted to investigate the effectiveness for randomly selected subjects are given in the accompanying table (based on "An Analysis of hypnotism in reducing pain. Results Factors That Contribute to the Efficacy of Hypnotic Analgesia," by Price and Barber, Journal of…arrow_forwardCONSTRUCT MODIFIED BOXPLOT To understand better the effects of exercise and aging on various cireulatory functions, the article "Cardiac Output in Male Middle-Aged Runners" (Journal of Sports Medicine [1982]: 17–22) presented data from a study of 21 middle-aged male runners. The following data set gives values of oxygen capacity values (in milliliters per kilo- gram per minute) while the participants pedaled at a speci- fied rate on a bicycle ergometer: 12.81 14.95 15.83 15.97 17.90 18.27 18.34 19.82 19.94 20.62 20.88 20.93 20.98 20.99 21.15 22.16 22.24 23.16 23.56 35.78 36.73 a. Compute the median and the quartiles for this data set. b. What is the value of the interquartile range? Are there outliers in this data set? c. Draw a modified boxplot, and comment on the interest- ing features of the plot.arrow_forwardA cohort study is conducted to assess the association between clinical characteristics and the risk of stroke. The study involves n=1,250 participants who are free of stroke at the study start. Each participant is assessed at study start (baseline) and every year thereafter for five years. The following table displays data on hypertensive status measured at baseline and incident stroke over 5 years. Free of Stroke over 5 Years Stroke Baseline: Not Hypertensive 952 46 Baseline: Hypertensive 234 18 Compute the cumulative incidence of stroke in the study.arrow_forward
- A cohort study is conducted to assess the association between clinical characteristics and the risk of stroke. The study involves n=1,250 participants who are free of stroke at the study start. Each participant is assessed at study start (baseline) and every year thereafter for five years. The following table displays data on hypertensive status measured at baseline and incident stroke over 5 years. Free of Stroke at 5 Years Stroke Baseline: Not Hypertensive 952 46 Baseline: Hypertensive 234 18 Compute the population attributable risk of stroke for patients with hypertension.arrow_forwardA cohort study is conducted to assess the association between clinical characteristics and the risk of stroke. The study involves n=1,250 participants who are free of stroke at the study start. Each participant is assessed at study start (baseline) and every year thereafter for five years. The following table displays data on hypertensive status measured at baseline and incident stroke over 5 years. Free of Stroke at 5 Years Stroke Baseline: Not Hypertensive 952 46 Baseline: Hypertensive 234 18 Compute the risk difference of stroke (per 5 person-years) for patients with hypertension as compared to patients free of hypertension.arrow_forwardA study published by Babcock and Marks (2010) showed that the average full-time U.S. college student studied for μ = 14 hours per week (SD = 4.8 hours per week) in 2005. We want to know if this average has changed in the past 15 years. In other words, we are going to do a study in which we try to determine whether there has been an impact of the passage of time on the amount of time college students spend studying. We selected a sample of n = 64 of today’s college students and find that they spent an average of M = 12.5 hours per week studying. Does this sample indicate a significant change in the number of hours spent studying? Use a two-tailed test (this means non-directional hypothesis) with α = .05.arrow_forward
- OphthalmologyRetinitis pigmentosa (RP) is a hereditary ocular diseasein which patches of pigment appear on the retina, potentially resulting in substantial vision loss and in somecases complete blindness. An important issue is how fastthe subjects decline. Visual field is an important measureof area of vision, which is measured in degree2. A visualfield area for a normal person is around 11,000 degree2.The longitudinal data in Table 11.29 were provided by anindividual patient.Table 11.29 Longitudinal visual field data forone RP patientTime Visual field area lnVisit (yr) (degree2) (visual field area)1 0 3059 8.032 1 3053 8.023 2 1418 7.264 3 1692 7.435 4 1978 7.596 5 1567 7.367 6 1919 7.568 7 1998 7.609 11 1648 7.4110 13 1721 7.4511 15 1264 7.14mean 6.09 1938 7.532sd 4.97 597 0.280Suppose the rate of change of ln (visual field) is a linearfunction of follow-up time.11.103 Write down a linear regression model that summarizes this relationship.11.104 Fit the regression line using…arrow_forwardNumber 2 pls.arrow_forwardRetinitis pigmentosa (RP) is a hereditary ocular diseasein which patches of pigment appear on the retina, potentially resulting in substantial vision loss and in somecases complete blindness. An important issue is how fastthe subjects decline. Visual field is an important measureof area of vision, which is measured in degree2. A visualfield area for a normal person is around 11,000 degree2.The longitudinal data in Table 11.29 were provided by anindividual patient.Table 11.29 Longitudinal visual field data forone RP patientTime Visual field area lnVisit (yr) (degree2) (visual field area)1 0 3059 8.032 1 3053 8.023 2 1418 7.264 3 1692 7.435 4 1978 7.596 5 1567 7.367 6 1919 7.568 7 1998 7.609 11 1648 7.4110 13 1721 7.4511 15 1264 7.14mean 6.09 1938 7.532sd 4.97 597 0.280Suppose the rate of change of ln (visual field) is a linearfunction of follow-up time.11.103 Write down a linear regression model that summarizes this relationship.arrow_forward
- Retinitis pigmentosa (RP) is a hereditary ocular diseasein which patches of pigment appear on the retina, potentially resulting in substantial vision loss and in somecases complete blindness. An important issue is how fastthe subjects decline. Visual field is an important measureof area of vision, which is measured in degree2. A visualfield area for a normal person is around 11,000 degree2.The longitudinal data in Table 11.29 were provided by anindividual patient.Table 11.29 Longitudinal visual field data forone RP patientTime Visual field area lnVisit (yr) (degree2) (visual field area)1 0 3059 8.032 1 3053 8.023 2 1418 7.264 3 1692 7.435 4 1978 7.596 5 1567 7.367 6 1919 7.568 7 1998 7.609 11 1648 7.4110 13 1721 7.4511 15 1264 7.14mean 6.09 1938 7.532sd 4.97 597 0.280Suppose the rate of change of ln (visual field) is a linearfunction of follow-up time.11.103 Write down a linear regression model that summarizes this relationship.11.104 Fit the regression line using the method of…arrow_forwardplease show diagram of p valuearrow_forwardCompute a 95% CI for the mean white blood countfollowing admission.arrow_forward
- Glencoe Algebra 1, Student Edition, 9780079039897...AlgebraISBN:9780079039897Author:CarterPublisher:McGraw Hill