GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
6th Edition
ISBN: 9781260239775
Author: BROOKER
Publisher: MCG
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Chapter 16, Problem 8CONQ
Summary Introduction

To review:

The process of gene silencing after X-chromosome inactivation (XCI) and give an example of a gene that does not get silenced.

Introduction:

XCI takes place to ensure that the gene expression in both the sexes, male and female, is equal. One of the two chromosomes in females gets heterochromatinized and forms a ‘Barr Body’. There is almost no expression of genes on this chromosome but sometimes, there might be some genes that show ‘leaky’ expression.

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Name something that could be happening to glutamate transporters that could have this effect on glutamate transport (i.e. the difference in glutamate transporters between control and experimental conditions). (Bonus: if you can also guess what the experimental condition is).
a. For the control condition, calculate Kd. Include units and show your work. b. For the control condition, calculate Bmax. Include units and show your work.  c. For the experimental condition, calculate Kd. Include units and show your work. For the experimental condition, calculate Bmax. Include units and show your work.
Now draw a rough sketch of what the control data might look like if in addition to the specific binding, there was also a considerable amount of nonspecific binding (again using a normal dose/response curve)

Chapter 16 Solutions

GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY