GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
6th Edition
ISBN: 9781260239775
Author: BROOKER
Publisher: MCG
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Chapter 16, Problem 7EQ
Summary Introduction

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The effect of lossfunction mutations in genes;FLC, VIN3, and COLDAIR when, CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR associated protein 9) technology is applied to the winter annual strain of Arabidopsis thaliana flowering and vernalizationrequirement by the plant.

Introduction:

Vernalization is a phenomenon in which, certain plant species prior to flowering are exposed to cold weather conditions. After the exposure plants acquire the ability to flower when exposed to favorable conditions. This becomes mandatory for certain plant species as it is essential to induce flowering in winter-annuals but not summer-annuals. Vernalization occurs in the tips of the plants that is, apical meristem.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 16 Solutions

GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY