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Interpretation:
The nucleophile in the reaction of an aldehyde or ketone with a Grignard reagent is to be identified, and the function of magnesium in the Grignard reagent and the product formed initially and after water is added are to be determined.
Concept Introduction:
>Electrophiles are electron deficient species which has positive or partially positive charge. Lewis acids are electrophiles which accept electron pair.
>Nucleophiles are electron rich species which has negative or partially negative charge. Lewis bases are nucleophiles which donate electron pair.
>Nucleophilic addition reaction is an addition reaction where electron deficient or electrophilic double or triple bond reacts with electron rich species (nucleophile), with disappearance of the double bond and creation of two single bonds.
>The Grignard reagent or RMgX is a polar organometallic reagent that undergoes nucleophilic addition reaction with
In nucleophilic addition, the negative part of the attacking reagent goes to electron deficient carbon and gets attached. The addition product then undergoes elimination to form the final product.
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Chapter 16 Solutions
Organic Chemistry
- OA. For the structure shown, rank the bond lengths (labeled a, b and c) from shortest to longest. Place your answer in the box. Only the answer in the box will be graded. (2 points) H -CH3 THe b Нarrow_forwardDon't used hand raitingarrow_forwardQuizzes - Gen Organic & Biological Che... ☆ myd21.lcc.edu + O G screenshot on mac - Google Search savings hulu youtube google disney+ HBO zlib Homework Hel...s | bartleby cell bio book Yuzu Reader: Chemistry G periodic table - Google Search b Home | bartleby 0:33:26 remaining CHEM 120 Chapter 5_Quiz 3 Page 1: 1 > 2 > 3 > 6 ¦ 5 > 4 > 7 ¦ 1 1 10 8 ¦ 9 a ¦ -- Quiz Information silicon-27 A doctor gives a patient 0.01 mC i of beta radiation. How many beta particles would the patient receive in I minute? (1 Ci = 3.7 x 10 10 d/s) Question 5 (1 point) Saved Listen 2.22 x 107 222 x 108 3.7 x 108 2.22 x 108 none of the above Question 6 (1 point) Listen The recommended dosage of 1-131 for a test is 4.2 μCi per kg of body mass. How many millicuries should be given to a 55 kg patient? (1 mCi = 1000 μСi)? 230 mCiarrow_forward
- Q4: Rank the relative nucleophilicity of halide ions in water solution and DMF solution, respectively. F CI Br | Q5: Determine which of the substrates will and will not react with NaSCH3 in an SN2 reaction to have a reasonable yield of product. NH2 Br Br Br .OH Brarrow_forwardClassify each molecule as optically active or inactive. Determine the configuration at each H соон Chirality center OH 애 He OH H3C Ноос H H COOH A K B.arrow_forwardQ1: Rank the relative nucleophilicity of the following species in ethanol. CH3O¯, CH3OH, CH3COO, CH3COOH, CH3S Q2: Group these solvents into either protic solvents or aprotic solvents. Acetonitrile (CH3CN), H₂O, Acetic acid (CH3COOH), Acetone (CH3COCH3), CH3CH2OH, DMSO (CH3SOCH3), DMF (HCON(CH3)2), CH3OHarrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning
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