Chapter 16, Problem 3Q

Summary Introduction

To determine:

The reason that why at the end of 1800s smallpox manifested as a much milder disease which had a high case fatality rate in 1500s.

Concept introduction

Smallpox is one of the infectious diseases caused by the virus. The causative agent of smallpox is Variola major and Variola minor virus. Small pox disease is characterized by the development of red color, itchy pustules on the face, neck, trunk, and all over the body, and high fever.