How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [ NADH ] [ NAD + ] in the mitochondrial matrix. Introduction: Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

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Answer 1

Question

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

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You’ve isolated a protein and determined that the Native molecular weight of the holoenzyme is 160 kD using size exclusion chromatography. Analysis of this protein using SDS-PAGE revealed 2 bands, one at 100 kD and one at 30 kD. The enzyme was found to be 0.829% NAD (by weight). What further can be said regarding the structure of the polypeptide?

Answer 2

Question

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

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Answer 3

Question

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

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Answer 4

Question

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

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Answer 5

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Answer 6

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Answer 7

Chapter 16, Problem 31P

Summary Introduction

To determine: How the citric acid cycle can be expected to respond to a rapid increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Answer 8

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Answer 9

Summary Introduction

To determine: The reason for the effect of increase in the ratio of [NADH][NAD+] in the mitochondrial matrix.

Introduction:

Citric acid cycle is the combination of various types of chemical reactions. Some reactions of the cycle are exergonic while some are endergonic in nature. Three exergonic steps of citric acid cycle are catalyzed by isocitrate dehydrogenase and α ketoglutarate dehydrogenase. Under some circumstances, these steps become the rate limiting steps.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 16 - Prob. 1P Ch. 16 - Prob. 2P Ch. 16 - Prob. 3P Ch. 16 - Prob. 4P Ch. 16 - Prob. 5P Ch. 16 - Prob. 6P Ch. 16 - Prob. 7P Ch. 16 - Prob. 8P Ch. 16 - Prob. 9P Ch. 16 - Prob. 10P

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