Biological Science (6th Edition)
Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 16, Problem 1TYK
Summary Introduction

Introduction:

A mutation refers to the permanent alteration of the DNA (deoxyribonucleic acid) sequence in an organism. The mutations can occur due to the insertion, deletion, or change in the base-pair of the DNA sequence.

Expert Solution & Answer
Check Mark

Answer to Problem 1TYK

Correct answer:

The change in the base pair during replication process is referred to as a mutation.

Explanation of Solution

Explanation/Justification for the correct answer:

Option (a) is given as a mutation. An alteration in the base-pair of the sequence during the DNA replication is a mutation because it is a permanent change that can affect the whole process of DNA replication. Moreover, it alters codon sequence that leads to formation of nonessential amino acids. Hence, Option (a) is correct.

Explanation for the incorrect answers:

Option (b) is given as mutations that fall in the protein-coding part of the gene. These mutations are known as missense mutations, which also come under mutations only. So, it is an incorrect option.

Option (c) is given as mutation in the transcribed part of the genome. Even, if the mutation does not fall in the protein-coding part or in the transcribed part of the genome, it would still be called as a mutation. So, it is an incorrect option.

Option (d) is given as single base-pair change is not considered as mutation. A change in a single base-pair has the potential to change the whole DNA sequence. Hence, a single base-pair change is also considered as a mutation. So, it is an incorrect option.

Hence, the options (b), (c), and (d) are incorrect.

Conclusion

A mutation is an alteration in the genome. The change in the base-pair of the DNA sequence is always considered as a mutation, no matter where it is present.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
Outline a method for using apomixis to maintain feminized CannabisAssume apomixis is controlled by a single dominant gene. You can choose the type of apomixis: obligate or facultative, gametophytic or sporophytic. Discuss advantages and disadvantages of your proposed method.
Kinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.  Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data  (b) k, ka, B1, and AUC* for the po data  c) k, ka, B1, and AUC* for the ip data  (d) relative bioavailability for po vs ip, Fpo/Fip  (e)absolute ip bioavailability, Fip  (f) absolute po bioavailability, Fpo
3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L.  Measurements from preliminary tests indicate the following human pharmacokinetic parameter values:  t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%.  Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax).  (c) Estimate the maximum plasma concentration (Cmax).  (d) Estimate the time at which the plasma level first rises above 30 mg/L.  (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L.  Hint:  based on part (a) it should be apparent that the answer is less than 1hr.)  (e)…
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Text book image
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Text book image
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
Text book image
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Text book image
BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
Biology
ISBN:9781305967359
Author:STARR
Publisher:CENGAGE L
Text book image
Body Structures & Functions Updated
Biology
ISBN:9780357191606
Author:Scott
Publisher:Cengage
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY