Pearson eText Microbiology: An Introduction -- Instant Access (Pearson+)
13th Edition
ISBN: 9780135789377
Author: Gerard Tortora, Berdell Funke
Publisher: PEARSON+
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Chapter 16, Problem 1MCQ
Summary Introduction
Introduction:
The complement system consists of thirty heat-labile proteins from plasma and is involved in the opsonization of pathogens for assisting the immune responses of the host. The complement proteins are protease in nature, which helps to cleave the antigens to neutralize the infectious substances. It is a cascade or a series of proteins (from C1 to C9 and some proteins are indicated as lower cases, a and b) that commence at the time of infection; the process is termed as complement activation.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 16 Solutions
Pearson eText Microbiology: An Introduction -- Instant Access (Pearson+)
Ch. 16 - Identify at least one physical and one chemical...Ch. 16 - Define inflammation, and list its characteristics.Ch. 16 - What are interferons? Discuss their roles in...Ch. 16 - How can the complement system cause endotoxic...Ch. 16 - Patients with X-linked chronic granulomatous...Ch. 16 - Prob. 6RCh. 16 - Give several examples of how microbes evade the...Ch. 16 - Prob. 8RCh. 16 - Are the following involved in innate or adaptive...Ch. 16 - These agranulocytes are not phagocytic until they...
Ch. 16 - Prob. 1MCQCh. 16 - Prob. 2MCQCh. 16 - If the following are placed in the order of...Ch. 16 - Prob. 4MCQCh. 16 - A human host can prevent a pathogen from getting...Ch. 16 - Prob. 6MCQCh. 16 - In 1884. Elie Metchnikoff observed blood cells...Ch. 16 - Prob. 8MCQCh. 16 - Prob. 9MCQCh. 16 - Prob. 10MCQCh. 16 - Prob. 1ACh. 16 - Prob. 2ACh. 16 - Prob. 3ACh. 16 - The list below identifies a virulence factor for a...Ch. 16 - People with Rhinovirus infections of the nose and...Ch. 16 - Prob. 2CAECh. 16 - Leukocyte adherence deficiency (LAD) is an...Ch. 16 - The neutrophils of individuals with Chdiak-Higashi...Ch. 16 - Consider the following. a. In laboratory...
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