EBK BIOLOGY
6th Edition
ISBN: 9780134819150
Author: Maier
Publisher: VST
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Chapter 16, Problem 1GFO
What species are endangered in the region where you live or go to school? Choose one of these species and determine what factors, such as loss of habitat or overhunting, have contributed to its population decline. What actions are being taken to protect this species from extinction? What, if anything, is being done to help the population recover?
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Chapter 16 Solutions
EBK BIOLOGY
Ch. 16 - Prob. 1LTBCh. 16 - Compare and contrast the species interactions of...Ch. 16 - Prob. 3LTBCh. 16 - Current rates of species extinction appear to be...Ch. 16 - According to the generalized species-area curve,...Ch. 16 - Prob. 6LTBCh. 16 - Prob. 7LTBCh. 16 - Which of the following is an example of a...Ch. 16 - Prob. 9LTBCh. 16 - Prob. 10LTB
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