Biology
Biology
4th Edition
ISBN: 9781259188121
Author: Peter Stiling, Robert Brooker, Linda Graham, Eric Widmaier
Publisher: McGraw-Hill Education
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Chapter 15.1, Problem 1BC
Summary Introduction

To describe: The role of checkpoint proteins in the prevention of cancer.

Introduction: Checkpoints help in regulating the process of the eukaryotic cell cycle. Checkpoint proteins synthesized at different checkpoints present in the eukaryotic cell cycle. These checkpoint proteins help in the prevention of cancer. Checkpoints are located at G1, G2 and M phases of eukaryotic cell cycle.

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Objective: To review the phases of mitosis with the understanding that in a real tissue or a non-synchronized cell culture, different mitotic phases and cells in interphase will be observed at a certain time. Interphase is the period between mitotic events; all other phases are part of mitosis and their individual probabilities add up to the total probability of seeing cells undergoing mitosis. Pay attention to the individual probabilities for cells in each phase of the cell cycle.   Problem N° 10 For a certain type of animal tissue, the probability of a randomly selected cell being in a particular stage of the interphase/mitosis cycle is given by the following table: Stage Probability Interphase 0.5   Prophase 0.1   Metaphase 0.05 Anaphase 0.2   Telophase 0.15 Suppose you examine 100 cells at random from this tissue. A)  How many cells do you expect to see in metaphase? _____ cells B) You have selected a high magnification (2000 X) in your…
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