Biology
4th Edition
ISBN: 9781259188121
Author: Peter Stiling, Robert Brooker, Linda Graham, Eric Widmaier
Publisher: McGraw-Hill Education
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Chapter 15, Problem 4TY
Summary Introduction
Introduction: The process of mitosis produces two genetically identical daughter cells. Mitosis can be also referred to the process of sorting in which one cell nucleus divides into two nuclei. The same complement of chromosomes is received by each daughter cell in mitosis.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 15 Solutions
Biology
Ch. 15.1 - Researchers usually treat cells with drugs that...Ch. 15.1 - Which phases make up interphase?Ch. 15.1 - Prob. 1BCCh. 15.1 - Prob. 1EQCh. 15.1 - The Eukaryotic Cell Cycle CoreSKILL What...Ch. 15.1 - Prob. 3EQCh. 15.2 - Prob. 1CCCh. 15.2 - Prob. 2CCCh. 15.2 - Mitotic Cell Division Concept Check: What are the...Ch. 15.3 - Prob. 1CC
Ch. 15.3 - Sexual Reproduction Concept Check: What is the...Ch. 15.4 - Variation in Chromosome Structure and Number...Ch. 15 - Prob. 1TYCh. 15 - Prob. 2TYCh. 15 - Prob. 3TYCh. 15 - Prob. 4TYCh. 15 - Prob. 5TYCh. 15 - Which of the following is not an event of anaphase...Ch. 15 - Prob. 7TYCh. 15 - Which of the following statements accurately...Ch. 15 - Prob. 9TYCh. 15 - Aneuploidy may be the result of a. duplication of...Ch. 15 - Prob. 1CQCh. 15 - Prob. 2CQCh. 15 - Prob. 3CQCh. 15 - Prob. 1COQCh. 15 - A diploid eukaryotic cell has 10 chromosomes (5...
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