Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

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Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

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Kinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration. Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e)absolute ip bioavailability, Fip (f) absolute po bioavailability, Fpo

3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax). (c) Estimate the maximum plasma concentration (Cmax). (d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.) (e)…

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Question

Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

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Answer 3

Question

Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

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Answer 4

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Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

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Answer 5

Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

Answer 6

Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

Answer 7

Chapter 15, Problem 6MCQ

Summary Introduction

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

Answer 8

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Ch. 15 - Compare pathogenicity with virulence.Ch. 15 - How are capsules and cell wall components related...Ch. 15 - Prob. 3R Ch. 15 - Explain how drugs that bind each of the following...Ch. 15 - Prob. 5R Ch. 15 - Prob. 6R Ch. 15 - Prob. 7R Ch. 15 - Which of the following genera is the most...Ch. 15 - How can viruses and protozoa avoid being killed by...Ch. 15 - Prob. 10R

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

Solution Summary: The author explains that capsules are a virulence factor which enhances the disease-causing ability of the bacteria.

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

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Chapter 15 Solutions

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

Solution Summary: The author explains that capsules are a virulence factor which enhances the disease-causing ability of the bacteria.

Introduction: Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.

Want to see the full answer?

Chapter 15 Solutions

Introduction:

Some of the bacteria enclose themselves by capsules formed of polysaccharides called encapsulated. These encapsulated stains of the bacteria are more virulent and resistant to intracellular killing than non-encapsulated stains.