Chapter 15, Problem 6CTQ

Summary Introduction

To explain:

The process by which superantigens, such as toxic shock syndrome toxin secreted by Staphylococcus aureus, often lead to the development of life-threatening symptoms in an infected individual.

Concept introduction:

Superantigens represent certain bacterial toxins, which are related to a group of immunogens and these are potent stimuli for T-cells. The presence of superantigens during an infection activates the T cells at a hundred times more than normal antigens. This resulted in an increased production of cytokines and cell death.