Microbiology: A Systems Approach
Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 15, Problem 1MCQ

The primary B-cell receptor is

  1. a. IgD.
  2. b. IgA.
  3. c. IgE.
  4. d. IgG.
Expert Solution & Answer
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Summary Introduction

Introduction:

Immunoglobulins are the glycoprotein molecules which are present in a Y shaped structure. They bind to the antigenic foreign epitopes and inhibit the spread of infection inside the human body. They are composed of one heavy chain and one light chain with variable and constant regions in the polypeptide protein.

Answer to Problem 1MCQ

Correct answer:

The primary B-cell receptor is IgD. Therefore, option (a) is correct.

Option (a) is given as “IgD”.

Explanation of Solution

Justify reason for the correct statement:

In the case of B lymphocytes, the genes code for Ig (immunoglobulins) synthesis, which are the receptors for B-cells. There are antigen binding sites in the ends of forks that are formed by the heavy and light chains and are variable in shape with respect to the shape of antigens. IgDis one of the classes of Igs that is secreted in blood and is present as a part of the membrane surface receptor molecule on B cells.

Hence, option (a) is correct.

Justify reasons for the incorrect statements:

Option (b) is given as “IgA”.

IgA is secreted in the lactating milk and forms the defense immunity in a child. It is not the primary Ig of B-cell receptors. Hence, it is a wrong answer.

Option (c) is given as “IgE”.

IgE is released from the mast cells following an antigenic response in the human body. It is not the primary Ig of B-cell receptors. Hence, it is a wrong answer.

Option (d) is given as “IgG”.

IgG is the antibody which is formed from activated B cells and circulates in the blood and body fluids. It is not the primary Ig of B-cell receptors. Hence, it is a wrong answer.

Hence, options (b),(c), and(d) are incorrect.

Conclusion

IgD is the immunoglobulin class that is considered as the primaryreceptor of B-cell.

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Chapter 15 Solutions

Microbiology: A Systems Approach

Ch. 15.3 - List characteristics of antigens that optimize...Ch. 15.3 - Prob. 12AYPCh. 15.3 - List the types of cells that can act as...Ch. 15.4 - Prob. 14AYPCh. 15.4 - Diagram the steps of B-cell activation, and list...Ch. 15.5 - Prob. 16AYPCh. 15.5 - Explain the role of cytotoxic T cells in...Ch. 15.6 - Diagram an antibody binding antigen, and list the...Ch. 15.6 - List the five types of antibodies and important...Ch. 15.6 - Draw and label a graph illustrating the...Ch. 15.7 - Prob. 21AYPCh. 15.7 - Discuss the qualities of an effective vaccine.Ch. 15.7 - List several types of vaccines, and discuss how...Ch. 15.7 - Explain the principle of herd immunity and the...Ch. 15 - The primary B-cell receptor is a. IgD. b. IgA. c....Ch. 15 - In humans. B cells mature in the _________, and T...Ch. 15 - Small, simple molecules are ________ antigens. a....Ch. 15 - The cross-linkage of antigens by antibodies is...Ch. 15 - T cells assist in the functions of certain B cells...Ch. 15 - TC cells are important in controlling a. virus...Ch. 15 - Which of the following can serve as...Ch. 15 - A vaccine that contains parts of viruses is called...Ch. 15 - Conjugated vaccines combine antigens and a....Ch. 15 - Widespread immunity that protects the population...Ch. 15 - Cell surface markers are also often called...Ch. 15 - Antibodies are secreted by monocytes.Ch. 15 - Vaccination could be described as artificial...Ch. 15 - IgE antibodies are found in body secretions.Ch. 15 - Prob. 15TFCh. 15 - Explain the two main features that characterize...Ch. 15 - Prob. 2CTQCh. 15 - Prob. 3CTQCh. 15 - Provide an explanation to refute the following...Ch. 15 - a. Explain how the anamnestic response is...Ch. 15 - Prob. 1VCCh. 15 - Using the words that follow, please create a...
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