PRINCIPLES OF LIFE W ACHIEVE
3rd Edition
ISBN: 9781319505370
Author: HILLIS
Publisher: MAC HIGHER
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Chapter 15, Problem 1.2Q
Summary Introduction
To determine: The ways by which the statement can be supported that large genomes don not result in complex organisms.
Introduction: The genetic material in all the living organism is the DNA (deoxyribonucleic acid). All the eukaryotes as well the prokaryotes have defined set of DNA sequence, which is inherited from one generation to another and codes for all the characters of the organism.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 15 Solutions
PRINCIPLES OF LIFE W ACHIEVE
Ch. 15.1 - Prob. 1LOCh. 15.1 - Prob. 2LOCh. 15.1 - Prob. 3LOCh. 15.1 - Prob. 4LOCh. 15.1 - Prob. 1ICh. 15.1 - Prob. 2ICh. 15.1 - Prob. 3ICh. 15.1 - Prob. 4ICh. 15.1 - Prob. 1RACh. 15.1 - Prob. 2RA
Ch. 15.1 - Prob. 3RACh. 15.1 - Prob. 4RACh. 15.2 - Prob. 1LOCh. 15.2 - Prob. 2LOCh. 15.2 - Prob. 3LOCh. 15.2 - Prob. 4LOCh. 15.2 - Prob. 1RACh. 15.2 - Prob. 2RACh. 15.2 - Prob. 3RACh. 15.2 - Prob. 4RACh. 15.3 - Prob. 1LOCh. 15.3 - Prob. 2LOCh. 15.3 - Prob. 3LOCh. 15.3 - Prob. 4LOCh. 15.3 - Prob. 1FQCh. 15.3 - Prob. 2FQCh. 15.3 - Prob. 3FQCh. 15.3 - Prob. 1RACh. 15.3 - Prob. 2RACh. 15.3 - Prob. 3RACh. 15.4 - Prob. 1LOCh. 15.4 - Prob. 2LOCh. 15.4 - Prob. 3LOCh. 15.4 - Prob. 1RACh. 15.4 - Prob. 2RACh. 15.4 - Prob. 3RACh. 15.4 - Prob. 1TKCh. 15.4 - Prob. 2TKCh. 15.4 - Prob. 3TKCh. 15.4 - Prob. 4TKCh. 15.4 - Prob. 5TKCh. 15.4 - Prob. 6TKCh. 15 - Prob. 1.1QCh. 15 - Prob. 1.2QCh. 15 - Prob. 1.3QCh. 15 - Prob. 2.1QCh. 15 - Prob. 2.2QCh. 15 - Prob. 2.3QCh. 15 - Prob. 3.1QCh. 15 - Prob. 3.2QCh. 15 - Prob. 3.3QCh. 15 - Prob. 4.1QCh. 15 - Prob. 4.2Q
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