Biology: The Unity and Diversity of Life (Looseleaf)
15th Edition
ISBN: 9781337408417
Author: STARR
Publisher: CENGAGE L
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Chapter 14, Problem 7GP
Expression of the SRY gene on the Y chromosome gives rise to the male
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Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the fact that one of the extra X Chromosome is inactivated practically leaving an XY active sex chromosomes similar to a normal male?
Males of many diploid species (like us) have X and Y sex chromosomes. They are hemizygous for most X-
linked genes. Thus, males express most X-linked alleles, whether they are dominant or recessive in
females. In the fruit fly Drosophila, it is common to achieve the equivalent of a test cross of X-linked
genes in females by assessing the readily observed phenotypes of their male progeny. Since males do
not receive X-linked genes from their father, sires of these crosses can be normal or wild-type flies. In fly
genetics, it is conventional to name a gene after the mutant phenotype that enabled its discovery.
Your challenge is to establish gene order and map distances between three X-linked genes in Drosophila.
Each gene is represented by recessive mutant alleles that express rather distinctive phenotypes relative
to their dominant wild-type alternative alleles. Flies expressing fruitless (f) are bisexual, lush (1) have a
heightened responses to ethanol, and ken&barbie (kb) lack external…
What is a Barr body?
How many Barr bodies in a person with genotype XXXXX?
How is the structure of a Barr body different from that of other chromosomes in the cell?
How does the structure of a Barr body affect gene expression?
Color-blindness is an X-linked recessive trait. Heterozygous females are not color blind but they can sometimes have partial color blindness. Explain how this can occur.
Chapter 14 Solutions
Biology: The Unity and Diversity of Life (Looseleaf)
Ch. 14 - Prob. 1DAACh. 14 - Prob. 2DAACh. 14 - Prob. 3DAACh. 14 - Prob. 4DAACh. 14 - Prob. 5DAACh. 14 - Prob. 1SQCh. 14 - Pedigree analysis is necessary when studying human...Ch. 14 - A recognized set of symptoms that characterize a...Ch. 14 - Prob. 4SQCh. 14 - A trait that is present in a male child but not in...
Ch. 14 - Choose the statement that is incorrect. a. A son...Ch. 14 - Prob. 7SQCh. 14 - Prob. 8SQCh. 14 - Klinefelter syndrome (XXY) can most be easily...Ch. 14 - Prob. 10SQCh. 14 - Does the phenotype indicated by the red circles...Ch. 14 - G6PD deficiency is an X-Linked recessive disorder....Ch. 14 - Marian syndrome (Section 13.5) is inherited in an...Ch. 14 - Duchenne muscular dystrophy, which is inherited in...Ch. 14 - Human females have two X chromosomes (XX); males...Ch. 14 - A mutation on an autosome causes a particular...Ch. 14 - Expression of the SRY gene on the Y chromosome...Ch. 14 - The somatic cells of most individuals with Down...Ch. 14 - Mutations in the genes for clotting factor VIII...
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- Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forwardWhat evidence indicates that a trait is coded by a dominant allele on an autosome?arrow_forwardHuman females have two X chromosomes XX; males have one X and one Y chromosome XY. a. With respect to X-linked alleles, how many different types of gametes can a male produce? b. A female homozygous for an X-linked allele can produce how many types of gametes with respect to that allele? c. A female heterozygous for an X-linked allele can produce how many types of gametes with respect to that allele?arrow_forward
- In humans color vision is X-linked, the gene for color vision is located on the X chromosome but is absent on the Y chromosome. Normal color vision (XN) is dominant over colorblindness (Xn). Suppose a colorblind man fathers the children of a woman with genotype XNXN. What is the genotype of the father? What proportion of daughters will be colorblind? What proportion of the sons will be colorblind?arrow_forwardLet’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During Metaphase, what will you observe in the somatic cells?arrow_forwardA family has an X-linked dominant form of congenital generalizedhypertrichosis (excessive hairiness). Although the allele is dominant,males are more severely affected than females. Moreover, the womenin the family often have asymmetrical, hairy patches on their bodies.How does X chromosome inactivation explain this observation?arrow_forward
- In humans, one of the genes determining color vision islocated on the X chromosome. The dominant form (C )produces normal color vision; red-green color deficiency(c) is recessive. If a man with normal color visionmarries a color-deficient woman, what is the probabilityof them having a color-deficient son? A color-deficientdaughter?arrow_forwardA company that offers PGD terms an embryo “normal and healthy” if it has 46 chromosomes. Why is this statement misleading? , Two famous male actors had twins using a surrogate mother who carried two embryos that hadbeen fertilized in vitro, one with one man’s sperm and the other with the other man’s sperm. In terms of genetics, how closely are the babies, a boy and a girl, related to each other if they have different fathers?arrow_forwardHumans have two different sex chromosomes, X and Y. Figure 4 below shows the inheritance of sex in humans. Figure 4 Mother Father XX XX Y XY XY a) Copy the diagram into your answer booklet and draw a circle on the part of Figure 4 that shows an egg cell. b) What is the genotype of the male offspring? c) A man and a woman have two sons. The woman is pregnant with a third child. What is the chance that this child will also be a boy?arrow_forward
- Part 2 Spotty and Cutie have puppies and 50% of the puppies are unaffected for both traits (not blind and not BHFD). What is Spotty's genotype? bbDD bbdd BBDd BbDd BbDD BBddarrow_forwardIn humans, color vision depends on genes encoding three pigments. The R (red pigment) and G (green pigment) genes are close together on the X chromosome, whereas the B (blue pigment) gene is autosomal. A recessive mutation in any one of these genes can cause color blindness. Suppose that a color-blind man married a woman with normal color vision. The four sons from this marriage were color-blind, and the five daughters were normal. Specify the most likely genotypes of both parents and their children, explaining your reasoning. (A pedigree drawing will probably be helpful.) (Problem 50 is by Rosemary Redfield.)arrow_forwardWhy is it that so many of the sex-linked traits we talk about in humans are carried on X chromosomes - but are expressed mostly in males?arrow_forward
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