EBK ESSENTIALS OF HUMAN ANATOMY & PHYSI
EBK ESSENTIALS OF HUMAN ANATOMY & PHYSI
12th Edition
ISBN: 8220103633604
Author: KELLER
Publisher: PEARSON
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Chapter 14, Problem 38SAE
Summary Introduction

To review:

The two different methods used for heat loss by the body.

Introduction:

When the food is oxidized, some of the energy is used for ATP (adenosine triphosphate) production and the rest is dissipated as heat by the body. This heat is used to maintain body temperature. Two heat loss mechanisms used by living body, which includes heat loss by radiation and heat loss by perspiration. Both these mechanisms are under the control of the hypothalamus in the brain.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 14 Solutions

EBK ESSENTIALS OF HUMAN ANATOMY & PHYSI

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