Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 14, Problem 25PDQ

Skin cancer carries a lifetime risk nearly equal to that of all other cancers combined. Following is a graph (modified from Kraemer, 1997. Proc. Natl. Acad. Sci. (USA) 94:11–14) depicting the age of onset of skin cancers in patients with or without XP, where cumulative percentage of skin cancer is plotted against age. The non-XP curve is based on 29,757 cancers surveyed by the National Cancer Institute, and the curve representing those with XP is based on 63 skin cancers from the XerodermaPigmentosum Registry.

(a) Provide an overview of the information contained in the graph.

(b) Explain why individuals with XP show such an early age of onset.

Chapter 14, Problem 25PDQ, Skin cancer carries a lifetime risk nearly equal to that of all other cancers combined. Following is

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