Campbell Biology in Focus
Campbell Biology in Focus
3rd Edition
ISBN: 9780134710679
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Rebecca Orr
Publisher: PEARSON
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Chapter 14, Problem 13TYU

SYNTHESIZE YOUR KNOWLEDGE

Chapter 14, Problem 13TYU, SYNTHESIZE YOUR KNOWLEDGE Some mutations result in proteins that function well at one temperature

Some mutations result in proteins that function well at one temperature but are nonfunctional at a different (usually higher) temperature. Siamese cats have such a “temperature-sensitive” mutation in a gene encoding an enzyme that makes dark pigment in the fur. The mutation results in the breed's distinctive point markings and lighter body color (see the photo). Using this information and what you learned in the chapter, explain the pattern of the cat’s fur pigmentation.

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You suspect a protein that is being expressed has been affected by a mutation.  When you examine the fully functional protein you find curiously that it still has retained all of its overall function.  A friend of yours doing research with you assures you when examining the genetic data a new mutation does in fact exist in this protein.  What is the most likely type of mutation that occurred based on this information?  Group of answer choices frameshift mutation silent mutation nonsense mutation
A gene affecting the behavioral outlook of individuals was discovered in several humans who can overcome anxiety caused by life's problems. Part of the gene that į translated into protein has a sequence 3'-GGATCCCGAATGTAATGCGTGCTC AATGGTAGTACGGC-5'. 1. What is the complementary strand of the DNA? 2. What is the sequence of the MRNA product after translation? 3. What is the sequence of the peptide encoded by the portion of the gene? (Use one letter symbol of amino acids)
Transcribe and translate the mutated sequence #1.  Determine the consequence, if any, for each mutation.  You will need to use your codon charts in your ISN.  Practice with both charts.

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